Postsclerotherapy Hyperpigmentations: A One‐Year Follow‐Up

Georgiev, Mihael

doi:10.1111/j.1524-4725.1990.tb00088.x

Cited by 45 publications

(23 citation statements)

References 2 publications

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“…The importance of optimal sclerotherapy practice, namely good injection technique, careful choice, strength of the sclerosant, prompt evacuation of retained blood, and adequate compression have been stressed by several authors 6,21 . Large diameter venulectasias are the vessels most likely to produce hyperpigmentation 13,22,23 .…”

Section: Discussionmentioning

confidence: 99%

“…One of the common complications of sclerotherapy of dilated lower limb veins is the occurrence of cutaneous pigmentation 1,2 . The incidence of pigmentation has reportedly varied between types of solutions used, 3–5 but techniques and concentrations of solutions injected may be more important factors 1,6 . Clinically the pigmentation usually occurs within the first 6 weeks following treatment and in most cases will fade spontaneously over the next 2 years with the vast majority fading within 6 months 7 .…”

mentioning

confidence: 99%

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Postsclerotherapy Hyperpigmentation

Thibault¹,

Wlodarczyk²

1992

The Journal of Dermatologic Surgery and Oncology

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Cutaneous pigmentation is a common complication of sclerotherapy of dilated lower limb veins. Histologic examination has shown that the pigment is due to hemosiderin deposition predominantly in the superficial dermis. Optimal technique will reduce the incidence of pigmentation but it is likely that patient factors such as total body iron storage may explain why some patients are more prone to develop pigmentation. Traditional exfoliation therapies have not given reliable reproducible results and there is need to develop an effective treatment without adverse sequelae. In this study 16 patients with refractory postsclerotherapy pigmentation were treated with the copper vapor laser. Within 3 months of treatment 11 (69%) had significant clearing of the pigmentation. Four (25%) had slight improvement and one patient had no discernible improvement. No adverse sequelae were reported or observed. The treated patients and 16 matched control patients who had not developed pigmentation were investigated with serum iron, ferritin and transferrin levels. There was a trend towards higher serum iron and ferritin levels and lower transferrin levels in the patients who developed pigmentation compared with those who did not develop this sequela. This trend was statistically significant for ferritin levels in patients 50 years of age and younger. The results indicate that serum ferritin may be a good indicator of susceptibility to postsclerotherapy pigmentation.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Postsclerotherapy Hyperpigmentation

Thibault¹,

Wlodarczyk²

1992

The Journal of Dermatologic Surgery and Oncology

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“…Die Häufigkeit von Hautnekrosen wird zwischen Hyperpigmentierungen nach Verödungsbehandlungen sind sehr verbreitet und werden in einer Häufigkeit zwischen 10 und 80% angegeben [25]. Die meisten dieser Hyperpigmentierungen sind innerhalb eines Jahres nicht mehr zu beobachten, lediglich 1% besteht über 1 Jahr hinaus [24]. Für eine Verödungstherapie der V. saphena magna oder parva besteht nur ausnahmsweise eine Indikation, wie weiter oben angegeben.…”

Section: Sklerotherapieunclassified

“…b Akute Thrombose der V. poplitea bei einer 25-jährigen Patientin nach längerer Autofahrt, operative Therapie0,01% und 0,2% angegeben. Das Auftreten einer allergischen Reaktion wird in einer australischen Studie mit 0,2% angegeben, wobei keine schwerwiegenden allergischen Rektionen wie ein anaphylaktischer Schock auftraten[8,24,25].…”

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Operative Prophylaxe und Therapie der chronisch venösen Insuffizienz

Eckstein

Noppeney²

2002

Der Internist

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“…CUTANEOUS HYPERPIGMENTATION that occurs after venous sclerotherapy is common and has been reported to last up to 6 months in 30% of patients, and more than 6 months in approximately 10% of patients treated with polydocanol (POL) 1–5 . The development of cutaneous hyperpigmentation is secondary to the sclerosing agent and the inflammatory reaction it incites.…”

mentioning

confidence: 99%