Postradiation dental extractions without hyperbaric oxygen

The effect of prior radiation therapy for treatment of nasopharyngeal cancer on wound healing following extractions: incidence of complications and risk factors

“…The incidence of ORN in the present study was 1.9%, which is comparable to the results of other studies 10,14 .The risk of DH of 5.8% is also similar to the 6.3% in another Asian population study 1 . For this study, only NPC patients were selected, as this is the commonest cancer in the local population to be treated with radiation therapy.…”

“…The risk of ORN has decreased significantly from 11.8% in the premegavoltage era (before 1968) to 5.4% in the postmegavoltage era 4 . Some recent studies showed extremely low incidences of ORN at 1.7%, 0.2% and 0% 1,9,14 , and DH at 6.3% 1 . This is predicted to decrease further with the increasing availability of 3D-conformal and intensity-modulated radiation therapy.…”

Prophylactic use of pentoxifylline and tocopherol in patients who require dental extractions after radiotherapy for cancer of the head and neck

“…Although several different regimens have been proposed, 14,[16][17][18][19][20][21] there is no consensus about which is most effective. In our study, 9 different regimens were prescribed for various reasons such as allergies, medical history, and previous drug history.…”

Incidence and prevention of osteoradionecrosis after dental extraction in irradiated patients: a systematic review

“…Most authors suggest extraction should be performed with minimal trauma or atraumatically to reduce the risk of developing ORN 28,42,45,50,59,73,74,78,81 .…”

“…Limiting the number of teeth to be extracted in a single session and using low-adrenaline local anesthesia or avoiding certain local anesthetic (LA) agents are also used 59 . These suggestions are based on years of clinical experience with the disease.…”