Postoperative spindle cell nodule after thyroidectomy: A case mimicking recurrence with anaplastic transformation of thyroid cancer

Kim, Sun Wook; Oh, Young Lyun; Choi, Joon Young; Lee, Ji In; Kim, Jee Soo

doi:10.1002/hed.21784

Cited by 8 publications

(11 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Microscopic examination revealed several important characteristics of PSCN (4,5), including intersecting fascicles of spindle cells, small blood vessels and various chronic inflammatory cells scattered in myxoid stroma. The spindle cells were arranged in bundles or nodules, which had compacted acidophilic cytoplasm and elongated, blunt-ended nuclei.…”

Section: Discussionmentioning

confidence: 99%

Postoperative spindle cell nodule of the bladder: A case report and review of the literature

2014

View full text Add to dashboard Cite

Postoperative spindle cell nodule (PSCN) of the bladder is a rare condition. It is a type of benign lesion frequently misdiagnosed as sarcomatoid carcinoma on the basis of similar cell morphology. The present report describes a tumor affecting a 71-year-old male who had undergone three transurethral resections. Pathological results suggested a diagnosis of sarcomatoid carcinoma, and therefore a radical cystectomy was performed. However, the tumor was later identified as a PSCN. In order to prevent such misdiagnosis, this study reviews relevant articles concerning postoperative spindle cell nodules of the bladder and compares PSCN and sarcomatoid carcinomas to identify specific characteristics of PSCN. Finally, the report emphasizes the importance of careful pathological examination in rare cases such as PSCN and sarcomatoid carcinoma.

show abstract

Section: Discussionmentioning

confidence: 99%

Postoperative spindle cell nodule of the bladder: A case report and review of the literature

2014

View full text Add to dashboard Cite

show abstract

“…Postoperative spindle cell nodules in the thyroidectomy bed are extremely rare 4. According to the literature, the reported sites of postoperative spindle cell nodule included the genitourinary tract, oral cavity, breast, and skin 1-3.…”

Section: Discussionmentioning

confidence: 99%

“…According to the literature, the reported sites of postoperative spindle cell nodule included the genitourinary tract, oral cavity, breast, and skin 1-3. Except for cases arising in the skin, all other cases have arisen in previous biopsy or operation sites,1-4 and the cases arising in the skin all had a history of trauma. In 1984, Proppe et al1 reported eight cases of spindle cell nodules with benign features arising in the lower genitourinary tract.…”

Section: Discussionmentioning

confidence: 99%

“…Metastatic or recurrent cancers should be also investigated in patients with a history of malignancy. Although there is one report of a postoperative spindle cell nodule in the thyroid bed after surgery,4 no articles describing cytologic findings were found. These cytologic findings are different from those for other spindle cell lesions, and are useful for differential diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…Although postoperative spindle cell nodules have occasionally been found in the lower genitourinary tract,1-3 their presence in post thyroidectomy sites has been reported in only one case 4. In addition, diagnosis by fine needle aspiration (FNA) has not been established.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Fine Needle Aspiration Cytology of Postoperative Spindle Cell Nodule in Neck after Thyroidectomy: A Case Report

Kang

Cho

et al. 2013

Korean J Pathol

View full text Add to dashboard Cite

Cytologic features of aggressive variants of follicular‐derived thyroid carcinoma

Rossi

Faquin

Pantanowitz

2019

Cancer Cytopathology

View full text Add to dashboard Cite

Certain carcinomas of the thyroid gland behave aggressively resulting in increased patient morbidity and poor patient prognosis. The diagnosis of these aggressive thyroid cancer subtypes is sometimes challenging and subject to increased interobserver variability. This review deals with the cytological features of such tumors including aggressive variants of papillary thyroid carcinoma, poorly differentiated thyroid carcinoma, and anaplastic thyroid carcinoma. These malignancies fall into 2 groups based on their cytomorphology: those that exhibit distinct microscopic features (eg, nuclear findings typical of classical papillary thyroid carcinoma or marked anaplasia) and those that present with more subtle cytologic features (eg, nuclear pseudostratification, “soap bubble” nuclei, supranuclear or subnuclear cytoplasmic vacuoles, rosette‐like structures, hobnail cells). We review the literature regarding these aggressive thyroid cancers and highlight important phenotypic characteristics that can be useful for their diagnosis based on fine needle aspiration.

show abstract

Postoperative spindle cell nodule after thyroidectomy: A case mimicking recurrence with anaplastic transformation of thyroid cancer

Abstract: Although postoperative spindle cell nodules are rare after thyroid surgery, it should be considered in the differential diagnosis for recurrent masses at the operative site.

Cited by 8 publications

References 15 publications

Postoperative spindle cell nodule of the bladder: A case report and review of the literature

Postoperative spindle cell nodule of the bladder: A case report and review of the literature

Fine Needle Aspiration Cytology of Postoperative Spindle Cell Nodule in Neck after Thyroidectomy: A Case Report

Cytologic features of aggressive variants of follicular‐derived thyroid carcinoma

Contact Info

Product

Resources

About