Postoperative Radiotherapy in the Treatment of Ewing Tumors: Influence of the Interval between Surgery and Radiotherapy

Abstract

Patients with early onset of postoperative irradiation show a trend for improved local control compared to patients with a later onset; the difference is statistically not significant. This trend has no influence on survival.

Whole Lung Irradiation in Patients with Exclusively Pulmonary Metastases of Ewing Tumors

“…All patients with pulmonary metastases reported here were defined as high-risk patients. Local therapy was performed as described elsewhere [18][19][20][21]. WLI was recommended in patients with pulmonary metastases at diagnosis even if a complete remission had been achieved after chemotherapy.…”

“…An independent trial radiotherapy reference center made recommendations for radiation portals, doses, and application of WLI or further boost irradiations. Additional details concerning local and systemic therapy have previously been published [9,[18][19][20][21].…”

Intraoperative Radiotherapy of Soft Tissue Sarcoma of the Extremity

“…Patients with Ewing's sarcoma (n = 156) treated in the CESS 86 and EICESS 92 trials were evaluated in a retrospective analysis [22]. No influence of the postoperative time interval before start of EBRT was found on local control rates or event-free survival.…”

Hyperfractionated 192Ir Brachytherapy for Recurrent Retroperitoneal Sarcoma: a Technique for Delivery of Local Tumor Boost Dose

“…Radical surgical resection is the mainstay of treatment, and patients with histologically complete tumor resection have a significantly improved prognosis over those with microscopically or macroscopically involved margins [11,15,22]. Irradiation significantly improves local tumor control in sarcoma [18,20,26]. The role of radiotherapy in retroperitoneal sarcoma, however, remains controversial.…”