1977
DOI: 10.1002/bjs.1800641008
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Postoperative pulmonary perfusion defects: their natural history, origin and significance

Abstract: Unmatched perfusion defects occur during the early postoperative period. These defects can persist until the tenth postoperative day and their presence is not related to the transfusion of blood or to peripheral thrombosis detected by the 125I-labelled fibrinogen uptake test. It is suggested that prophylactic agents against deep venous thrombosis should be evaluated by using a combination of krypton ventilation-perfusion lung scans and 125I-labelled fibrinogen leg scans.

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Cited by 8 publications
(3 citation statements)
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“…This is a much lower figure than previous workers have reported (Browse et al, 1974(Browse et al, , 1976 but is in agreement with Knight and Metrevelli (1977). The low incidence in Knight and Metrevelli's patients might be explained by the fact that 11 of the 26 patients studied underwent hernia repair, a group of patients in whom thromboembolism rarely occurs.…”
Section: Discussionsupporting
confidence: 85%
“…This is a much lower figure than previous workers have reported (Browse et al, 1974(Browse et al, , 1976 but is in agreement with Knight and Metrevelli (1977). The low incidence in Knight and Metrevelli's patients might be explained by the fact that 11 of the 26 patients studied underwent hernia repair, a group of patients in whom thromboembolism rarely occurs.…”
Section: Discussionsupporting
confidence: 85%
“…This figure is almost certainly too low, however, as l25I-fibrinogen labelling and routine lung scanning were not employed [Kakkar et al, 1975;Knight and Metrewelli, 1977], We found evidence of an acute confusional state post-operatively in almost 1 in 10 of our elderly surgical patients, which is sim ilar to the incidence of 14% reported in a recent prospective study by Millar [1981]. Palmberg and Hirsjarvi [1981] estimated that 11.2% of their elderly patients developed post-operative confusional states and sugested that such patients might be at higher risk of developing dementia in later years.…”
Section: Post-operative Morbidity In the Agedcomparison With Previousmentioning
confidence: 99%
“…These results are consistent with those of McNEIL (1976). KNIGHT & METREWELLI (1977) found no correlation between the presence of perfusion defects without defects also in ventilation and deep vein thrombosis as demonstrated by 125I-fibrinogen scanning of the legs in a postoperative series. However, this does not mean that such perfusion defects may not be due to pulmonary embolism, since 125I-fibrinogen scanning is unable to detect thrombosis in the central veins in the leg above the middle of the thigh, i.e.…”
Section: Discussionmentioning
confidence: 63%