Postoperative pancreatitis

White, Michael; Morgan, Alan; Hopton, David

doi:10.1016/s0002-9610(70)80100-3

Cited by 103 publications

(14 citation statements)

References 4 publications

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“…22 The aetiological relevance of steroids is disputed;4 23 nearly half our patients on steroids had other predisposing factors. Our data suggest that diabetes is no more prevalent in acute pancreatitis than in the general population despite a previous report to the contrary.20 Pre-existing diabetes, however, does increase the risk of death from 19 to 43%.…”

Section: Aetiologymentioning

confidence: 93%

Acute pancreatitis: a lethal disease of increasing incidence.

Corfield¹,

Cooper²,

Williamson³

1985

Gut

295

137

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SUMMARY Between 1968 and 1979 650 patients in the Bristol clinical area suffered 737 attacks of acute pancreatitis. Sex distribution was approximately equal and mean age was 60 years.Comparison with the previous decade shows an increase in mean annual incidence of first attacks from 53 8 to 73-0 cases per million population. Case mortality was unchanged at 20%. In no less than 35% of fatal cases the diagnosis was first made at necropsy. Gall stones were detected in 50% of first attacks, predominantly in women. The proportion of alcoholics (8% overall) increased three-fold during the period of the study. In 23% of cases no aetiological cause was identified. Eighty patients suffered 99 recurrent attacks of acute pancreatitis, with a mortality rate (12%) that was not significantly lower than that of the first attack. Neglected gall stones accounted for 51% of these subsequent attacks.Wide differences in the incidence of acute pancreatitis have been reported both within and between countries. Bristol area presenting between 1 January 1968 and 31 December 1979 were assessed. An overlap with the earlier review for 1968 and 1969 was necessary, as patients presenting during these years had not been included in the previous statistical analysis. As before, several approaches were used to maximise case retrieval. The hospital activity analysis of the South Western Regional Health Authority was used to identify most cases; all the hospitals serving the Bristol clinical area were included in the computer search. The analysis coding used was 577.0 (acute pancreatitis), and the same code was used to calculate national returns for both incidence and mortality rate. A search of the death certificate records at the Coroner's office revealed a small number of otherwise unrecorded cases. Lastly, during the period under review various clinical trials in acute pancreatitis have been undertaken in Bristol,5 6 and details from these were included.

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Section: Aetiologymentioning

confidence: 93%

Acute pancreatitis: a lethal disease of increasing incidence.

Corfield¹,

Cooper²,

Williamson³

1985

Gut

295

137

View full text Add to dashboard Cite

show abstract

“…No significant differences were found when patients with pancreatitis, who were operated on within 48 hours of presentation to the hospital, were compared with patients operated on following more than 48 hours of hospitalization (Table 7). 1.8%, and 12.2% following common duct explora¬ tion. In the present study, the incidence of pancreatitis following cholecystectomy was found to be 0.6%, and follow¬ ing common duct exploration, it was 8.4%.…”

Section: Methodsmentioning

confidence: 97%

Pancreatitis After Biliary Tract Surgery

Vernava

Andrus

Herrmann³

et al. 1987

Arch Surg

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“…It is likely, therefore, that the general surgical trauma, or the colangiography itself together with this favorable factor (a deficiency of di-antitrypsin enzyme) provoked the onset of the postoperative pancreatitis [13,14],…”

Section: ]mentioning

confidence: 99%