Postoperative Outcome after Coronary Artery Bypass Grafting in Chronic Obstructive Pulmonary Disease

Manganas, H.; Lacasse, Yves; Bourgeois, Stéphanie; Perron, Jean; Dagenais, François; Maltais, François

doi:10.1155/2007/378963

Cited by 70 publications

(74 citation statements)

References 28 publications

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“…When postoperative results of severe COPD patients (FEV 1 less than 50% and FEV 1 / FVC less than 0.7) were compared with that of the mild-to-moderate COPD patients (FEV 1 50% and over, FEV 1 /FVC less than 0.7) and the ones with normal pulmonary functions, it was found that apart from increased pulmonary infection risk, inclination to postoperative atrial fibrillation and a bit increased hospitalization duration, the results were similar. Similar to the study of Mangenes et al, our study also established that moderate-advanced COPD did not carry a risk in terms of mortality and in fact, mortality was seen to be higher in the in mild-moderate COPD (Group 1) when compared with the moderate-advanced COPD (Group 2) [3]. These findings and results make us think that there are other factors affecting mortality independent of COPD stages in COPD patients on whom coronary artery surgery is performed.…”

Section: Discussionsupporting

confidence: 89%

“…With the impact of this last study, the detection of moderate or advanced COPD in preoperative evaluation was accepted a risk for mortality. However, in recent years, it has been found in a study by Mangenes et al that CABG surgery can be performed without increased mortality risk when severe COPD patients were compared with mild-to-moderate COPD patients and the ones with normal respiratory functions [3]. When postoperative results of severe COPD patients (FEV 1 less than 50% and FEV 1 / FVC less than 0.7) were compared with that of the mild-to-moderate COPD patients (FEV 1 50% and over, FEV 1 /FVC less than 0.7) and the ones with normal pulmonary functions, it was found that apart from increased pulmonary infection risk, inclination to postoperative atrial fibrillation and a bit increased hospitalization duration, the results were similar.…”

Section: Discussionmentioning

confidence: 99%

“…Mortality reaching up to 50% was found in studies carried out in the past years and the presence of COPD created unrest [2]. However, in recent years, preoperative intense therapies, use of more efficient medication and showing more sensitivity to patients with COPD have decreased mortality and morbidity [3].…”

Section: Introductionmentioning

confidence: 99%

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Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

İlhan¹,

Günay

Özkan

et al. 2016

Turk Toraks Dergisi

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OBJECTIVES:We aimed to investigate the impact of arterial blood gas (ABG) on morbidity and mortality in chronic obstructive pulmonary disease (COPD) patients undergoing CABG surgery. MATERIAL AND METHODS:The records for 75 COPD patients who underwent elective CABG surgery our institution clinic between November 2008 to 2011 and had a forced expiratory volume in 1 second (FEV 1 ) /forced vital capacity (FVC) ≤ 70% value in the pulmonary function tests (PFT) performed prior to the surgery were evaluated retrospectively. COPD patients were divided into two groups; Group 1; FEV 1 ≥ 60% and Group 2; FEV 1 ≤ 59%. Groups were compared for mortality and adverse events after identification of other preoperative and postoperative factors that could affect mortality and adverse events. An ABG was obtained immediately before and 3 to 6 hours after surgery to study the predictive value of ABG in seperate COPD groups. RESULTS:There were no significant differences in patients with high partial pressure carbondioxide (PaCO 2 ) preoperative values compared to patients with normal values. Also there were no significant differences in patients with lower partial pressure of oxygen (PaO 2 ) preoperative values compared to patients with normal values in terms of mortality. Postoperative myocardial infarction (MI) was significantly higher in patients with low PaO 2 values (p< 0.05). CONCLUSION:In conclusion, in our study, there could not be found a relation between the degree of preoperative obstruction and mortality for COPD patients who underwent CABG surgery. ABG was not found useful for predicting mortality in COPD patients undergoing CABG surgery, but could be useful to predict postoperative MI in patients with COPD.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

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Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

İlhan¹,

Günay

Özkan

et al. 2016

Turk Toraks Dergisi

View full text Add to dashboard Cite

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“…Our observation that patients with COPD were older and had a worse cardiovascular profi le than patients without COPD is consistent with fi the results of other investigations. 8,[14][15][16] Patients with COPD were more likely to have presented with dyspnea than with chest pain (62% vs 47%). Shortness of breath is a common symptom of COPD, and it may be interpreted as part of an acute exacerbation; as such, the diagnosis of an AMI can be missed.…”

Section: Discussionmentioning

confidence: 99%

The Impact of COPD on Management and Outcomes of Patients Hospitalized With Acute Myocardial Infarction

Stefan

Bannuru

Lessard

et al. 2012

Chest

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Our results suggest that the gap in medical care between patients with and without COPD hospitalized with AMI narrowed substantially between 1997 and 2007. Patients with COPD, however, remain less aggressively treated and are at increased risk for hospital adverse outcomes than patients without COPD in the setting of AMI. Careful consideration is necessary to ensure that these high-risk complex patients are not denied the benefits of effective cardiac therapies.

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“…The age difference between the two groups were not statistically significant (p=0.258) which are consistent with the study done by Lizak and colleagues, Manganas and colleagues. 6,7 In Group-I, 52% patients were smoker, 56% had hypertension, 28% had DM, 24% had hyperlipidemia and 32% had family history of IHD. In Group-II, 60% patients were smoker, 44% had hypertension, 32% had DM, 28% had hyperlipidemia and 44% had family history of IHD.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Pulmonary Function after Off-pump Coronary Artery Bypass Grafting in Patients Treated with Preoperative Bronchodilator

et al. 2015

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Background: Bronchodilators, by dilatation of bronchial tree through relaxation of bronchial smooth muscle increases the vital capacity, tidal volume and total lung capacity and reduces gas trapping. This study was conducted to assess the pulmonary function after off-pump coronary artery bypass graft (CABG) surgery between patients with impaired pulmonary function treated with or without preoperative bronchodilator. We also compared duration of mechanical ventilation and days spent in the surgical intensive care unit (ICU) after CABG in both group of patients. Methods: This prospective cohort study was carried out in the department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from July 2009 to April 2011. This study included 50 patients (25 patients in each group) with multi-vessels coronary artery disease with impaired pulmonary function who underwent off-pump CABG. Results: Spirometry was done in both groups of patients after admission, day before operation and on 7th post-operative day. The difference in Forced vital capacity (FVC) and Forced expiratory volume in 1st second (FEV1 ) between two groups were not statistically significant after admission (P>0.05). On the day before surgery the values of FVC and FEV1 were increased (more in Group-I who were treated with bronchodilator) and 7th postoperative day the values were decreased (more in Group-II who were not treated with bronchodilator). The results were found statistically significant in between groups (P<0.05). Conclusion: Bronchodilator should be considered pre-operatively in all patients having impaired pulmonary function undergoing off-pump CABG for better preservation of postoperative pulmonary function. DOI: http://dx.doi.org/10.3329/cardio.v7i2.22260 Cardiovasc. j. 2015; 7(2): 123-127

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Postoperative Outcome after Coronary Artery Bypass Grafting in Chronic Obstructive Pulmonary Disease

Abstract: Mortality rate associated with CABG surgery is not influenced by the presence and severity of airflow obstruction in patients with COPD. The incidence of pulmonary infections and length of hospital stay were increased in patients with severe COPD.

Cited by 70 publications

References 28 publications

Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

The Impact of COPD on Management and Outcomes of Patients Hospitalized With Acute Myocardial Infarction

Evaluation of Pulmonary Function after Off-pump Coronary Artery Bypass Grafting in Patients Treated with Preoperative Bronchodilator

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