Postoperative Atrial Fibrillation

Yadava, Mrinal; Hughey, Andrew B.; Crawford, Thomas

doi:10.1016/j.ccl.2014.07.002

Cited by 44 publications

(26 citation statements)

References 115 publications

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“…Miyokardiyal atriyal fibrozis AF'ye eşlik eden sık bulgudur. En sık tetikleyen alanlar, sol pulmoner venlere uzanan atriyal miyokard yastıkları, pulmoner venlerin histolojik, anatomik ve elektrofizyolojik özellikleri bu bölgedeki aritmojenik aktiviteye katkıda bulunur [2,3,10] .…”

Section: Patofizyolojiunclassified

“…Yine sempatik ve parasempatik stimülasyon (artmış otomasite, uyarılmış aktivite) AF'a neden olabilir [2,3] .…”

Section: Patofizyolojiunclassified

“…Diğer kalp tarafından üretilen proinflamatuar sitokinler IL 18 ve IL 1 β'dir. Proinflamatuar sitokinler POAF ile ilişkili bulunmuştur [3,12] .…”

Section: Patofizyolojiunclassified

“…Ancak AKK ve KPB zamanı ile aritmi insidansı arasın-da çelişkili bildirimler de bulunmaktadır. Yetersiz atriyal soğuma da atriyal fibrilasyonu tetikleyebilir [3] . KPB altında yapılan cerrahi sırasında antegrad + redrograd kardiyopleji uygulaması ile daha iyi bir miyokardiyal koruma sağlanabilir [15] .…”

Section: Patofizyolojiunclassified

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Atrial Fibrillation After Cardiac Surgery

Aksun¹,

Eryilmaz²,

Gürbüz³

et al. 2017

GKDA Derg

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Section: Patofizyolojiunclassified

“…Yine sempatik ve parasempatik stimülasyon (artmış otomasite, uyarılmış aktivite) AF'a neden olabilir [2,3] .…”

Section: Patofizyolojiunclassified

“…Diğer kalp tarafından üretilen proinflamatuar sitokinler IL 18 ve IL 1 β'dir. Proinflamatuar sitokinler POAF ile ilişkili bulunmuştur [3,12] .…”

Section: Patofizyolojiunclassified

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Atrial Fibrillation After Cardiac Surgery

Aksun¹,

Eryilmaz²,

Gürbüz³

et al. 2017

GKDA Derg

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show abstract

“…Atrial trauma after cannulation, acute atrial enlargement with pressure and volume, postoperative electrolyte disturbances, pericarditis, right coronary artery (RCA) grafting, having valvular heart disease, increased sympathetic activity, and beta-blocker discontinuation have been suggested to play etiological roles in the development of POAF (4). Age, hypertension, male sex, RCA stenosis, depressed left ventricular function, and a history of previous AF are important clinical variables related to the development of POAF (4). Bypass with valve replacement, prolonged aortic clamp time, and prolonged bypass time are major risk factors for the development of POAF (5).…”

Section: Introductionmentioning

confidence: 99%

Role of red blood cell distribution width and epicardial fat in atrial fibrillation after cardiopulmonary bypass

et al. 2018

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Objective: Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, and it remains a challenge for cardiac surgeons despite advances in medicine. A number of studies have been performed to examine various parameters to predict which patients will develop POAF. The present study was performed to investigate the roles of epicardial adipose tissue (EAT) volume and red blood cell distribution width (RDW) as predictors of POAF. Methods: The medical records of 350 patients undergoing coronary artery bypass grafting in one or more vessels at the Tertiary Cardiac Center, Cardiovascular Surgery Department, Mevlana (Rumi) University Private Hospital (Konya, Turkey), were screened between December 2011 and May 2015. The study population consisted of 149 patients fulfilling the inclusion criteria and undergoing a preoperative evaluation by computed chest tomography. All patient demographics and laboratory parameters were obtained from medical records. Results: Age, postoperative RDW, and tomography variables, including the left atrial (LA) volume, LA diameters, and EAT volume, were significantly higher while the hemoglobin level and hematocrit were significantly lower in patients developing atrial fibrillation after cardiopulmonary bypass. A logistic multivariate regression analysis was performed on age, postoperative RDW, and tomography variables, including LA volume, LA diameters and EAT volume. Only age (OR 1.0731, 95% CI 1.012-1.138; p = 0.018) was an independent predictor of the development of POAF. Conclusions: Although the EAT volume was high in patients developing atrial fibrillation after surgery, age was the only significant predictor of POAF on multivariate analysis. Additional studies regarding the predictive roles of epicardial fat and RDW in POAF are needed.

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Perioperative Amiodarone to Prevent Atrial fibrillation after Septal Myectomy in obstrUctive hypeRtroPHic cardiomyopathy

et al. 2021

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Aims Amiodarone reduces the incidence of atrial fibrillation (AF) following coronary artery bypass surgery; however, the benefit of perioperative amiodarone in patients undergoing septal myectomy (SM) for obstructive hypertrophic cardiomyopathy (oHCM) has not been studied. We hypothesized that prophylactic amiodarone would reduce the incidence of postoperative AF (POAF) following SM for oHCM. Methods and Results A single‐centre, pre‐post intervention open‐label study of oral amiodarone (200 mg twice daily starting 7 days preoperatively and 200 mg once daily continuing for 30 days postoperatively) in patients without prior AF undergoing SM for oHCM from 2014 to 2018. The primary outcome was incident AF within 30 days. Secondary outcomes were unplanned readmission, AF treatment, total and intensive care unit (ICU) length of stay (LOS), and pacemaker implantation for high‐grade atrioventricular (AV) block. 61 patients met inclusion criteria with 34 (55.8%) in the pre‐intervention (control) group and 27 (44.2%) in the post‐intervention (amiodarone) group. The incidence of POAF was 11.0% in the amiodarone group compared with 38.2% in the control group (P = 0.017). After adjusting for age, amiodarone was associated with less POAF [adjusted odds ratio (aOR) 0.21; 95% confidence interval (CI) 0.05, 0.76; P = 0.016]. ICU (2 days [IQR 1, 4] vs. 3 days [IQR 2, 4]; P = 0.165) and total (6 days [IQR 5, 6] vs. 6 days [IQR 5, 7]; P = 0.165) LOS were similar, as was the rate of pacemaker implantation (7.4% vs. 8.3%, P > 0.999). There were no adverse events associated with amiodarone. Conclusions Perioperative oral amiodarone is safe and was associated with lower incidence of POAF following SM for oHCM.

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Postoperative Atrial Fibrillation

Cited by 44 publications

References 115 publications

Atrial Fibrillation After Cardiac Surgery

Atrial Fibrillation After Cardiac Surgery

Role of red blood cell distribution width and epicardial fat in atrial fibrillation after cardiopulmonary bypass

Perioperative Amiodarone to Prevent Atrial fibrillation after Septal Myectomy in obstrUctive hypeRtroPHic cardiomyopathy

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