Postnatal neurogenesis in the telencephalon of turtles: evidence for nonradial migration of new neurons from distant proliferative ventricular zones to the olfactory bulbs

Pérez-Cañellas, Mar; Font, Enrique; García‐Verdugo, José Manuel

doi:10.1016/s0165-3806(97)00058-8

Cited by 53 publications

(50 citation statements)

References 47 publications

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“…In mammals, only microneurons are produced postnatally (Altman and Das, 1965). Many new neurons born in the brain of reptiles and birds are large and some are projecting neurons (Nottebohm, 1985(Nottebohm, , 1989Ló pez-García et al, 1988;Pérez-Cañellas and García-Verdugo, 1996;Pérez-Cañellas et al, 1997). We also found neurogenesis in many brainstem motor nuclei containing large neurons in goldfish.…”

Section: Discussionsupporting

confidence: 53%

“…In contrast, adult neurogenesis is observed in the olfactory bulb, dorsal telencephalon, optic tectum, cerebellum, and the brainstem in fish (Zupanc, 2006). Neurons born in adulthood have been reported in all the major subdivisions of the lacertilian telencephalon, including the olfactory bulbs (main and accessory), all of the four cortical areas (medial cortex, dorsomedial cortex, dorsal cortex, and lateral cortex), septum, anterior dorsal ventricular ridge, striatum, and nucleus sphericus (Ló pez-García et al, 1988;Pérez-Cañellas and García-Verdugo, 1996;Font et al, 1997;Pérez-Cañellas et al, 1997). The cerebellum may also be a site of adult neurogenesis in some reptiles (Ló pez-García et al, 1990).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Neurogenic and Neuroendocrine Effects of Goldfish Pheromones

Chung-Davidson¹,

Rees²,

Bryan³

et al. 2008

J. Neurosci.

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Neurogenic and Neuroendocrine Effects of Goldfish Pheromones

Chung-Davidson¹,

Rees²,

Bryan³

et al. 2008

J. Neurosci.

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“…These changes might be due to alterations in the neurogenic requirements of the mammalian telencephalon at postnatal stages. Since, apparently, in physiological conditions, adult mammals need to generate only olfactory bulb interneurons, which in all vertebrates use a specialized form of glial tracks Curtis et al 2007;Doetsch and Scharff 2001;Perez-Canellas et al 1997); progenitor cells no longer need a long basal process to guide the migration of newly-generated neurons. Notably, in vertebrates that undergo widespread adult neurogenesis, like fish, reptiles and amphibians, radial glia persists during adult life Alvarez-Buylla 1990;Chapouton et al 2006;Echeverri and Tanaka 2002;Garcia-Verdugo et al 2002;Grandel et al 2006).…”

Section: Adult Subependymal Stem Cellsmentioning

confidence: 99%

Radial glia and neural stem cells

2007

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During the last decade, the role of radial glia has been radically revisited. Rather than being considered a mere structural component serving to guide newborn neurons towards their final destinations, radial glia is now known to be the main source of neurons in several regions of the central nervous system, notably in the cerebral cortex. Radial glial cells differentiate from neuroepithelial progenitors at the beginning of neurogenesis and share with their ancestors the bipolar shape and the expression of some molecular markers. Radial glia, however, can be distinguished from neuroepithelial progenitors by the expression of astroglial markers. Clonal analyses showed that radial glia is a heterogeneous population, comprising both pluripotent and different lineage-restricted neural progenitors. At late-embryonic and postnatal stages, radial glial cells give rise to the neural stem cells responsible for adult neurogenesis. Embryonic pluripotent radial glia and adult neural stem cells may be clonally linked, thus representing a lineage displaying stem cell features in both the developing and mature central nervous system.

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“…However, in the Tarentola mauritanica, the majority of newborn cells seemed to be incorporated into MC (Perez-Canellas & Garcia-Verdugo 1996), which is considered as an area homologous to dentate gyrus of hippocampus in mammals on grounds of their anatomy, cyto-and chemoarchitecture and postnatal development (Lopez-Garcia et al 1992;Nacher et al 1996), and closely involved with learning and memory (Day et al 2001;Rodriguez et al 2002); DVR in Trachemys scrypta was found to show the most intensive labeling accumulation (Perez-Canellas et al 1997). It is possible that these interspecific differences may depend on behavioral patterns induced by distinct environmental stimuli.…”

Section: Regional and Interspecific Differences In Adult Neurogenesismentioning

confidence: 99%

Characterization of adult neurogenesis in lizardPhrynocephalus vlangalii(Agamidae: Reptilia)

Shao

Fan

et al. 2012

Italian Journal of Zoology

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Adult neurogenesis, a process of giving rise to neurons and glia from progenitors residing in restricted regions of the adult central nervous system (CNS) throughout life, varies considerably across species. The role of adult neurogenesis in reptiles, the amniotic vertebrates that possess spontaneous regenerative capacity is less known. In the present study, we used Phrynocephalus vlangalii -a typical reptile in northwest of China to investigate the cell proliferation and general pattern of glial fibrillary acidic protein (GFAP)-immunoreactivity in the brain of lizard. Compared with mammals, the brains of P. vlangaliiowned have simpler cytoarchitectonical patterns but a more widespread neurogenesis. Bromodeoxyuridine (BrdU)-labeled cells were mostly distributed in the ventricular zone of lateral ventricle with cell proliferation highest in the region referred to as anterior olfactory nucleus (AON). In addition, GFAP-immunostaining demonstrated differences in element, abundance and distribution. GFAP-positive cells were fundamentally represented by radial glial structures in telencephalon, diencephalon and mesencephalon. Furthermore, an intriguing finding was the emergence of GFAP-positive, star-shaped cells in the mesencephalon. We conclude that the cell proliferation and corresponding functions of glial lineage cells in lizards are closely implicated with phylogenetic development. Hence, reptiles provide excellent access for extracting core mechanisms of adult neurogenesis, which lays a good foundation to study the effect of different stimuli and exposure on the adult neurogenesis of reptiles.

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Postnatal neurogenesis in the telencephalon of turtles: evidence for nonradial migration of new neurons from distant proliferative ventricular zones to the olfactory bulbs

Cited by 53 publications

References 47 publications

Neurogenic and Neuroendocrine Effects of Goldfish Pheromones

Neurogenic and Neuroendocrine Effects of Goldfish Pheromones

Radial glia and neural stem cells

Characterization of adult neurogenesis in lizardPhrynocephalus vlangalii(Agamidae: Reptilia)

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