Posterior Cricoarytenoid Muscle Denervation

Kano, Shingo; Horowitz, Jay B.; Sasaki, Clarence T.

doi:10.1001/archotol.1991.01870210091018

Cited by 20 publications

(13 citation statements)

References 12 publications

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“…Furthermore, it possesses more motor fibers than a single branch of ansa cervicalis, and can produces more adequate reinnervation [14]; 2) laryngeal muscle may still retain an ability to receive regenerating nerve axons even after long-term denervation [25], [26]. Our previous study revealed that within 2 years after denervation, the laryngeal muscles exhibited a persistent regenerative potential for delayed laryngeal reinnervation from the viewpoint of muscle stem cells [27].…”

Section: Discussionmentioning

confidence: 99%

Laryngeal Reinnervation Using Ansa Cervicalis for Thyroid Surgery-Related Unilateral Vocal Fold Paralysis: A Long-Term Outcome Analysis of 237 Cases

Wang

Chen

et al. 2011

PLoS ONE

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ObjectiveTo evaluate the long-term efficacy of delayed laryngeal reinnervation using the main branch of the ansa cervicalis in treatment of unilateral vocal fold paralysis (UVFP) caused by thyroid surgery.Summary of Background DataUVFP remains a serious complication of thyroid surgery. Up to now, a completely satisfactory surgical treatment of UVFP has been elusive.MethodsFrom Jan. 1996 to Jan. 2008, a total of 237 UVFP patients who underwent ansa cervicalis main branch-to-recurrent laryngeal nerve (RLN) anastomosis were enrolled as UVFP group; another 237 age- and gender-matched normal subjects served as control group. Videostroboscopy, vocal function assessment (acoustic analysis, perceptual evaluation and maximum phonation time), and electromyography were performed preoperatively and postoperatively. The mean follow-up period was 5.2±2.7 years, ranging from 2 to 12 years.ResultsAnalysis of videostroboscopic findings indicated that the glottic closure, vocal fold edge, vocal fold position, phase symmetry and regularity were significantly improved in the UVFP group (P<0.001, postoperative vs. preoperative). The postoperative parameters of vocal function were also significantly improved in the UVFP group (P<0.001) and showed no statistical differences compared to the control group (P>0.05, respectively). Postoperative laryngeal electromyography confirmed successful reinnervation of laryngeal muscle.ConclusionsDelayed laryngeal reinnervation with the main branch of ansa cervicalis is a feasible and effective approach for treatment of thyroid surgery-related UVFP; it can restore the physiological laryngeal phonatory function to the normal or a nearly normal voice quality.

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Section: Discussionmentioning

confidence: 99%

Laryngeal Reinnervation Using Ansa Cervicalis for Thyroid Surgery-Related Unilateral Vocal Fold Paralysis: A Long-Term Outcome Analysis of 237 Cases

Wang

Chen

et al. 2011

PLoS ONE

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“…For example, Kano et al 10 reported that the posterior cricoarytenoid (PCA) muscle does not undergo atrophy for at least 1 year after nerve injury. However, Zealear et al 11 reported fibrosis of one third of PCA muscle fibers within 7 months of denervation.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous regeneration of recurrent laryngeal nerve following long‐term vocal fold paralysis in humans: Histologic evidence

Chen

Wang

et al. 2011

The Laryngoscope

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“…In a similar manner, this study demonstrated that early intervention with electrical stimulation will protect a muscle from deterioration. In the absence of intervention, cases where fibrosis has not occurred for long periods of time following denervation have been largely attributed to spontaneous reinnervation of the muscle by nonspecific nerve sources [14][15][16].…”

Section: Discussionmentioning

confidence: 99%

The Effects of Chronic Electrical Stimulation on Laryngeal Muscle Physiology and Histochemistry

Zealear

Billante

Chongkolwatana

et al. 2000

ORL

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The present study examined the effects of functional neuromuscular stimulation (FNS) on posterior cricoarytenoid (PCA) muscle physiology and histochemistry. In 4 canines, 10 cm of the recurrent laryngeal nerve was resected. A patch electrode array was implanted for PCA stimulation. FNS was applied to 2 canines for a period of 4 weeks with 2 additional animals serving as nonstimulated controls. Results indicated that FNS increased PCA muscle contractility over the period of intervention but had no effect on contraction speed. FNS also protected the muscle from atrophy by preventing muscle weight loss and type 2 fiber deterioration. Finally, it rescued muscle fibers from ensuing fibrosis.

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Posterior Cricoarytenoid Muscle Denervation

Cited by 20 publications

References 12 publications

Laryngeal Reinnervation Using Ansa Cervicalis for Thyroid Surgery-Related Unilateral Vocal Fold Paralysis: A Long-Term Outcome Analysis of 237 Cases

Laryngeal Reinnervation Using Ansa Cervicalis for Thyroid Surgery-Related Unilateral Vocal Fold Paralysis: A Long-Term Outcome Analysis of 237 Cases

Spontaneous regeneration of recurrent laryngeal nerve following long‐term vocal fold paralysis in humans: Histologic evidence

The Effects of Chronic Electrical Stimulation on Laryngeal Muscle Physiology and Histochemistry

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