Postadolescent Acne in Females

Holzmann, Ruth D.; Shakery, Kaweh

doi:10.1159/000354887

Cited by 68 publications

(77 citation statements)

References 29 publications

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“…Two main subtypes of adult acne can be identified: persistent adolescent acne (80% of cases) and late-onset acne (20% of cases), with first symptoms appearing well after puberty, usually about the age of 21–25 [6]. Both types are frequently associated with inflammation, hyperpigmentation and scarring [7].…”

Section: Introductionmentioning

confidence: 99%

The possible role of diet in the pathogenesis of adult female acne

Romańska-Gocka¹,

Woźniak²,

Kaczmarek-Skamira³

et al. 2016

pdia

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Acne in adults is a chronic, increasingly common disease, especially among women. It differs in pathogenesis and clinical presentation from adolescent acne. Acne in adults is associated with Western diet, defined as high consumption of milk, high glycemic load and high calorie intake. Metabolic signals of this diet result in a significant increase in insulin/insulin growth factor 1 serum level and consequently in the molecular interplay of mammalian target of rapamycin complex 1 kinase (mTORC1)/forkhead box protein 1 (FoxO1) mediated nutrient signaling, leading to increased proliferation of keratinocytes, increased lipogenesis and sebum production and finally to aggravation of acne.

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Section: Introductionmentioning

confidence: 99%

The possible role of diet in the pathogenesis of adult female acne

Romańska-Gocka¹,

Woźniak²,

Kaczmarek-Skamira³

et al. 2016

pdia

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“…10 For reasons that remain poorly understood, postadolescent acne is more common in women than in men. [5][6][7] Acne was one of three skin conditions in the top 10 most prevalent diseases worldwide in 2010. 11 However, the most widely used treatments have changed little in the past 30 years.…”

Section: Strengths and Limitations Of This Studymentioning

confidence: 99%

“…So far, no PSP has targeted a disease with peak prevalence during adolescence in mainly healthy subjects. Although acne is starting earlier 4 and lasting longer, [5][6][7] possibly as a result of lifestyle changes, peak prevalence is between the ages of 16 and 20 years. 8 9 The age range of acne now spans five decades; few…”

Section: Introductionmentioning

confidence: 99%

Identifying acne treatment uncertainties via a James Lind Alliance Priority Setting Partnership

et al. 2015

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ObjectivesThe Acne Priority Setting Partnership (PSP) was set up to identify and rank treatment uncertainties by bringing together people with acne, and professionals providing care within and beyond the National Health Service (NHS).SettingThe UK with international participation.ParticipantsTeenagers and adults with acne, parents, partners, nurses, clinicians, pharmacists, private practitioners.MethodsTreatment uncertainties were collected via separate online harvesting surveys, embedded within the PSP website, for patients and professionals. A wide variety of approaches were used to promote the surveys to stakeholder groups with a particular emphasis on teenagers and young adults. Survey submissions were collated using keywords and verified as uncertainties by appraising existing evidence. The 30 most popular themes were ranked via weighted scores from an online vote. At a priority setting workshop, patients and professionals discussed the 18 highest-scoring questions from the vote, and reached consensus on the top 10.ResultsIn the harvesting survey, 2310 people, including 652 professionals and 1456 patients (58% aged 24 y or younger), made submissions containing at least one research question. After checking for relevance and rephrasing, a total of 6255 questions were collated into themes. Valid votes ranking the 30 most common themes were obtained from 2807 participants. The top 10 uncertainties prioritised at the workshop were largely focused on management strategies, optimum use of common prescription medications and the role of non-drug based interventions. More female than male patients took part in the harvesting surveys and vote. A wider range of uncertainties were provided by patients compared to professionals.ConclusionsEngaging teenagers and young adults in priority setting is achievable using a variety of promotional methods. The top 10 uncertainties reveal an extensive knowledge gap about widely used interventions and the relative merits of drug versus non-drug based treatments in acne management.

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“…Yaş grupları gözetilmediğinde prevalansı %80 olarak bildirilmektedir, özellikle adölesanları etkilemekle birlikte erişkin dönemde de izlenebilmektedir [1][2][3] . Akne prevalansı genellikle 15-18 yaş arasında pik yapar, sonraki yıllarda hızlı bir gerileme gösterir.…”

Section: Introductionunclassified

“…Erkeklerde ergenlik sonrası 20-25 yaş arasında genellikle lezyonlar gerilerken, kadınlarda erişkin dönemde 40 yaşa kadar akne gelişmeye devam edebilmektedir [4][5][6] . Erişkin akneli olguların %80'i persistan akneden oluşurken, geri kalan %20'si 18 yaşından sonra yeni başlangıç göstermektedir 1,7 . Mevcut yayınlanmış veriler adölesan ve erişkin dönem akne arasındaki farklılıkları net olarak ortaya koyamasa da, klinik bulgular dolayısıyla bu iki durumun patogenezinin farklı olduğu düşünülmektedir.…”

Section: Introductionunclassified

Evaluation of hyperandrogenemia and metabolic risk profile in women with postadolescent acne

Selçuk¹,

Arıca²,

Yaylı³

2016

TURKDERM

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Background and Design: Postadolescent acne is a disease with relapses frequently seen in women. Treatment is difficult. In our study, we aimed to investigate the clinical and biochemical characteristics of hyperandrogenism and the prevalence of metabolic disorders, such as metabolic syndrome (MS) and dyslipidemia in women with postadolescent acne. Materials and Methods: This study was conducted on 50 women who attended our department with the complaint of postadolescent acne between July 2014 and December 2014. The presence of androgenetic alopecia (AGA), hirsutism, polycystic ovary syndrome (PCOS), MS, dyslipidemia, and obesity was evaluated. Results: Seborrhea was present in 56%, hirsutism in 40%, AGA in 26%, and PCOS in 24% of women with postadolescent acne. The prevalence of MS and dyslipidemia was 24% and 44%, respectively. The prevalence of MS was significantly higher in patients with AGA and hirsutism. There was no association of MS with menstrual irregularity and PCOS. There was no significant association of dyslipidemia with AGA, hirsutism, PCOS, and menstrual irregularity. Conclusion: Clinical symptoms of hyperandrogenism, such as hirsutism, AGA, and PCOS were more common in women with postadolescent acne but androgenic hormone profile abnormalities were minimal. As a result, postadolescent acne resistant to treatment may be considered as an early marker in the early diagnosis of PCOS in women to prevent the development of type 2 diabetes mellitus, MS and hypercholesterolemia.

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Postadolescent Acne in Females

Cited by 68 publications

References 29 publications

The possible role of diet in the pathogenesis of adult female acne

The possible role of diet in the pathogenesis of adult female acne

Identifying acne treatment uncertainties via a James Lind Alliance Priority Setting Partnership

Evaluation of hyperandrogenemia and metabolic risk profile in women with postadolescent acne

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