The possible role of diet in the pathogenesis of adult female acne

Romańska-Gocka, Krystyna; Woźniak, Magdalena; Kaczmarek-Skamira, Elżbieta; Zegarska, Barbara

doi:10.5114/ada.2016.63880

Cited by 29 publications

(26 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…While, serum TC, HDL, and LDL showed no significant difference between both studied groups. Concerning IR level in postadolescent acne patients, our result was in accordance with two studies 17,18 and opposed by only one study. 19 This difference is due to the fact that in the latter study, the studied groups were on low glycemic diet for at least 2 weeks prior to HOAM-IR test, which was not the case in the current study.…”

Section: Discussionsupporting

confidence: 91%

Impact of low ghrelin level in patients with postadolescent acne

Esaway

2019

J of Cosmetic Dermatology

View full text Add to dashboard Cite

Summary Background Ghrelin is a 28 amino acid peptide predominantly produced by the stomach. There are many putative roles for ghrelin beyond homeostatic appetite control. Aim of the work To determine ghrelin's level in postadolescent acne and study its relationship to plasma lipid profile, IR and acne severity and to correlate variables. Patients and methods This is a case‐control study where 50 patients with postadolescent acne and 50 age‐sex compatible controls were enrolled. Acne severity was assessed according to the Hayashi acne grading criteria. The parameters measured were serum level of ghrelin, fasting blood glucose, total cholesterol, low‐density lipoprotein, high‐density lipoprotein, triglycerides, and insulin. Results The mean serum level of Ghrelin was significantly lower in patients compared to control group and acne severity had a significant effect on ghrelin's level. Serum levels of insulin, fasting glucose, HOMA‐IR, and TG were significantly increased in patients group compared to control. Serum TC, HDL, and LDL showed no significant difference between both studied groups. Ghrelin hormone had a positive correlation to HDL and a negative correlation to BMI, LDL, HOMA‐IR, and Insulin. Conclusion This study postulated that low level of ghrelin may predispose patients with postadolescent acne to hyperinsulinemia, type 2 diabetes or dyslipidemia.

show abstract

Section: Discussionsupporting

confidence: 91%

Impact of low ghrelin level in patients with postadolescent acne

Esaway

2019

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…It is a multifactorial disease, originating in the pilosebaceous unit. Although much research has been conducted on acne, the aetiology of acne vulgaris remains poorly understood [ 1 – 4 ]. The current view is that acne is related to factors such as androgen, hyperseborrhea, hyperkeratosis of the pilosebaceous ducts, follicular orifice blockage, and proliferation of bacteria, such as Propionibacterium acnes , and Staphylococcus epidermidis [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

Demodex spp. as a possible aetiopathogenic factor of acne and relation with acne severity and type

Akçınar¹,

Ünal²,

Al³

2018

pdia

View full text Add to dashboard Cite

IntroductionAcne is a very common skin disease in adolescents and young adults, but it also affects adults. However, its aetiology is not yet fully understood. Demodex appears to be associated with multiple skin disorders, but controversy persists. Some reports indicate a connection between acne vulgaris and demodicosis.AimTo confirm the association between Demodex infestation and acne vulgaris.Material and methodsA total of 108 patients were enrolled in the acne group. Acne severity was calculated as GASS and acne type (adolescent and post adolescent) was recorded. An age-sex matched healthy control group comprising 65 individuals were included in the study. Dermatological examinations were performed and an SSSB was used to determine the presence of Demodex.ResultsIn our study, Demodex positivity was seen in 46 (42.6%) patients in the acne group and 8 (12.3%) in the control group; this difference was statistically significant (p < 0.001). A multivariate Backward Step-By-Step Logistic Regression analysis identified the most effective factors for acne development such as Demodex positivity (OR = 5.565, 95% CI: 2.384–12.99 and p < 0.001) and age under 25 years (OR = 2.3 and 95% CI: 1.183–4.473 and p = 0.014). Alcohol consumption was related to Demodex positivity (p = 0.019) in post adolescent acne.ConclusionsOur study is the first one to evaluate acne severity, acne type and the relationship to Demodex prevalence. We suggest that Demodex infestation should be considered when the classical therapies are ineffective especially in cases of post adolescent acne.

show abstract

“…In recent studies, apart from the consumption frequency of foodstuffs with high glycemic index values, the consumption frequency of certain foodstuffs with low glycemic index value was also found to be high in AV patients. 16,34,35 In this regard, we found that acne is triggered by foodstuff such as feta, cola, cheese, and peanut in which insulin index value was higher than glycemic index value. This result may suggest that insulin index may be used as another marker for AV-triggering foodstuffs.…”

Section: Case Control a Total Of 3826 Acne Vulgaris Patients And 759 mentioning

confidence: 85%