Post vaccination antibody titres of hepatitis B surface antigen (anti-HBs) in a mixed cohort of health care workers

Lall, Mahima; Sen, Sourav; Patrikar, Seema; Karade, Santosh; Gupta, R.M.

doi:10.1016/j.mjafi.2020.11.023

Cited by 3 publications

(6 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Studies have demonstrated a greater sero-conversion (80-90%) immediate post vaccination with hepatitis B vaccine and a decline over time. 31 Barash et al in their study observed that 40% of the study participants had their antibody titres evaluated with more than three fourth (77%) demonstrating protective titres over a time. These findings are in agreement with that of the present study.…”

Section: Discussionmentioning

confidence: 92%

Health care workers and Hepatitis B prevention: Perceptions and practices in a tertiary care hospital in coastal Karnataka

Eshwari¹,

Shenoy²,

Nair³

2022

Clinical Epidemiology and Global Health

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 92%

Health care workers and Hepatitis B prevention: Perceptions and practices in a tertiary care hospital in coastal Karnataka

Eshwari¹,

Shenoy²,

Nair³

2022

Clinical Epidemiology and Global Health

View full text Add to dashboard Cite

“…19 The duration of antibody titres against the HBsAg was declined after vaccination was increased and the increasing age was associated with falling protective titres. 4 In the present study, 100 subjects have been selected based on the HBV vaccination with completion of three doses. A similar study was also observed in Dehradun and Kerala with the involvement of 84-86% of fully vaccinated and 14-16% were partially vaccinated.…”

Section: Resultsmentioning

confidence: 99%

“…Globally, move forward towards the elimination of hepatic viral infections which was indorsed at 69 th World Health Assembly, approved by the "global health sector strategy to eliminate viral hepatitis by 2030". 4 Hepatitis B virus is a causative agent of hepatitis as well as chronic liver failure. Chronic infections arise in 5% of cases who become carriers and one quarter of these carriers which leads to hepatic cirrhosis and hepatocellular carcinoma.…”

Section: Introductionmentioning

confidence: 99%

“…Chronic infections arise in 5% of cases who become carriers and one quarter of these carriers which leads to hepatic cirrhosis and hepatocellular carcinoma. 4 Most of the developing countries like Bulgaria and India have major threat to HBV. [2][3][4][5][6] Since, CDC has recommended HBV vaccination for all HCWs from 1997.…”

Section: Introductionmentioning

confidence: 99%

“…4 Most of the developing countries like Bulgaria and India have major threat to HBV. [2][3][4][5][6] Since, CDC has recommended HBV vaccination for all HCWs from 1997. HBV vaccinated among healthcare workers varies from 67-79% in developed and 18-35% in developing countries.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A prospective study on the quantification of anti-HBs antibody titers of vaccinated health care workers in a tertiary care teaching hospital by using automated enzyme linked fluorescent assay

Indernath¹,

Sudha²,

Shanmugavadivoo³

et al. 2022

Int J Community Med Public Health

View full text Add to dashboard Cite

Background: Hepatitis B virus (HBV) infection poses a major health problem among health care workers (HCWs). Globally, 350 million peoples have infected, and it was estimated by WHO. CDC has recommended HBV vaccination for all health care workers. The objective was to determine the anti-HBs antibodies titres among health care workers using automated enzyme linked fluorescent assay (ELFA).Methods: This prospective study was conducted in department of microbiology, tertiary care hospital. The test samples have been collected from health care workers who have completed the course of vaccination. VIDAS anti-HBs total II (AHBS) assay was initiated according to the manufacturer’s instructions.Results: Out of 100 subjects, 62% showed positive for anti-HBs antibodies and the remaining 38% showed negative. Positivity of anti-HBs antibody titers ranges from 27 mIU/ml to 500 mIU/ml.Conclusions: In the present study, 100 subjects have been selected based on the HBV vaccination with completion of three doses of vaccination. Presence of anti-HBs antibodies titers against the vaccination is fully immunized. The study was determined the vaccinated status of anti-HBs antibodies against the infection among clinicians, nurses and CRRIs and it has to be revealed at regular intervals of every 6 to 8 months.

show abstract

SENSITIVITAS DAN SPESIFISITAS METODE RAPID TEST ANTI-HBs TERHADAP ELISA

Putri

Santosa

2022

BMJ

View full text Add to dashboard Cite

Hepatitis B merupakan penyakit inflamasi dan nekrosis sel hati yang disebabkan oleh infeksi virus hepatitis B (VHB). Kehadiran anti-HBs merupakan faktor penting dalam diagnosis dan prognosis infeksi VHB. Rapid test adalah salah satu metode pemeriksaan selain ELISA untuk mendeteksi adanya anti-HBs, lebih praktis dalam penggunaan dan ekonomis. Tujuan penelitian ini untuk mengetahui nilai sensitivitas dan spesifisitas rapid test anti-HBs Intec® terhadap metode ELISA sebagai gold standar. Penelitian ini merupakan studi observasional menggunakan metode uji diagnostik. Populasi penelitian ini adalah mahasiswa D4 Analis Kesehatan FIKKES Universitas Muhammadiyah Semarang semester tujuh post vaksinasi hepatitis B sejumlah 32 orang untuk didapatkan serum darah. Analisis statistik dilakukan uji Mc Nemar. Hasil pemeriksaan dengan rapid test yaitu positif 26 sampel (81,2%), dan negatif 6 sampel (18,8%). Hasil pemeriksaan dengan ELISA yaitu reaktif 27 sampel (84,4%), dan nonreaktif 5 sampel (15,6%). Kesimpulan akhir yaitu Rapid test anti-HBs Intec® memiliki nilai sensitivitas dan spesifisitas yang sangat baik dengan persentase sensitivitas 96,3% dan persentase spesifisitas 100%. Tidak terdapat perbedaan yang bermakna pada sensitivitas dan spesifisitas metode rapid test dan ELISA (p= 1,000) sehingga Rapid test anti-HBs Intec® dapat digunakan sebagai skrining untuk pemeriksaan anti-HBs.

show abstract

Post vaccination antibody titres of hepatitis B surface antigen (anti-HBs) in a mixed cohort of health care workers

Cited by 3 publications

References 28 publications

Health care workers and Hepatitis B prevention: Perceptions and practices in a tertiary care hospital in coastal Karnataka

Health care workers and Hepatitis B prevention: Perceptions and practices in a tertiary care hospital in coastal Karnataka

A prospective study on the quantification of anti-HBs antibody titers of vaccinated health care workers in a tertiary care teaching hospital by using automated enzyme linked fluorescent assay

SENSITIVITAS DAN SPESIFISITAS METODE RAPID TEST ANTI-HBs TERHADAP ELISA

Contact Info

Product

Resources

About