2008
DOI: 10.1016/j.actbio.2008.05.015
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Post-self-assembly experimentation on extruded collagen fibres for tissue engineering applications

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Cited by 59 publications
(49 citation statements)
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References 107 publications
(156 reference statements)
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“…Currently, extensive efforts are being made to develop protein-based biomaterials for biomedical applications [1,2]. Having similar macromolecular structures to naturally occurring proteins in tissues and organs, protein-based biomaterials have the potential to provide biological functionality and can be degraded by natural enzymes and metabolized by physiological mechanisms [3].…”
Section: Introductionmentioning
confidence: 99%
“…Currently, extensive efforts are being made to develop protein-based biomaterials for biomedical applications [1,2]. Having similar macromolecular structures to naturally occurring proteins in tissues and organs, protein-based biomaterials have the potential to provide biological functionality and can be degraded by natural enzymes and metabolized by physiological mechanisms [3].…”
Section: Introductionmentioning
confidence: 99%
“…Collagen alignment along the isoelectric point occurred after supplying 20 VDC to the electrochemical cell equipped with a 1 megaohm resistor. Immediately after alignment, aligned collagen threads were incubated at 37 1C in 50 mL of 1X PBS (Uquillas et al, 2011) (Sigma-Aldrich, St. Louis, MO) for 6 h. After phosphate incubation, the aligned collagen threads were immersed in 20 mL of pure isopropyl alcohol (Zeugolis et al, 2008b) for 6 h. The threads were then washed with copious amounts of ultrapure water for 20 min. The isopropyl alcohol-free threads were laid over a nonsticking surface and fixed at both ends with tape.…”
Section: Elac Fabricationmentioning
confidence: 99%
“…When hydrogel contraction is restrained, fibroblasts are under tension. Then, they differentiate into myofibroblasts and adopt a synthetic phenotype [32,33]. Another example is the influence of the biomaterial stiffness on chondrocyte phenotype.…”
Section: Interactions Of Cells With Collagenmentioning
confidence: 99%