Post‐<scp>COVID</scp>‐19 Myoclonus‐Ataxia Syndrome—Is there Really a Need for Intravenous Immunoglobulin Treatment in all Cases?

Przytuła, Filip; Sławek, Jarosław

doi:10.1002/mdc3.13695

Cited by 3 publications

(2 citation statements)

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“…Treatment with corticosteroids seems to be equally effective, but significantly cheaper and more readily available than IVIG therapy. Therefore, we suggest starting with steroids and only in a case of non-responsiveness or contraindications following this treatment with IVIG [47].…”

Section: Ataxia/myoclonus/opsoclonus Syndromementioning

confidence: 99%

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Hyperkinetic movement disorders following SARS-CoV-2 infection and vaccination — an update

Przytuła¹,

Sławek

2023

Neurol Neurochir Pol.

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The aim of this review was to summarise current knowledge regarding hyperkinetic movement disorders related to SARS-CoV-2 infection and vaccination in terms of phenomenology, epidemiology, pathogenesis and treatment. After a thorough review of the PubMed and Google Scholar databases (2020-2022), we identified myoclonus and ataxia sometimes accompanied by opsoclonus (AMS) as the two most frequent COVID-19 sequelae, with chorea, tremor and dystonia being very rare. The pathogenesis seems to be variable, but in the majority of AMS cases it was autoimmunological, with good response and recovery after corticosteroids or intravenous immunoglobulins infusions. Vaccination may be complicated by hyperkinetic movement disorders (e.g. tremor, dystonia), but this is very rare. Patients with Deep Brain Simulation depletion should not be postponed due to lockdowns as this may result in fatal outcomes.

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Section: Ataxia/myoclonus/opsoclonus Syndromementioning

confidence: 99%

“…3). Apart from these reports, tremor coexisted in 17 patients with ataxia-myoclonus syndrome (AMS), opsoclonus-myoclonus-ataxia syndrome (OMAS), and opsoclonus-myoclonus syndrome (OMS)limb tremor four [13,22,44,45], voice tremor in nine [10,15,23,27], and limb tremor combined with voice tremor in four [25,26,44,47] (Tab. 1).…”

Section: Tremormentioning

confidence: 99%