Chorea following SARS-CoV-2 infection and vaccination: a systematic review of reported cases

Rosca, Elena Cecilia; Bilavu, Raluca; Cornea, Amalia; Simu, Mihaela

doi:10.1016/j.ijid.2023.07.001

Cited by 5 publications

(1 citation statement)

References 13 publications

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“…Aside from paraneoplastic cases, the trigger for autoimmune chorea is often unknown. There have been a small number of case reports of chorea and hemichorea occurring after COVID‐19 vaccination and infection, 6 including at least two corticosteroid‐responsive cases associated with the same Pfizer‐BioNTech COVID‐19 vaccine that our patient received. 7 , 8 Many of these cases were associated with encephalopathy.…”

Section: Discussionmentioning

confidence: 99%

A case of immunotherapy‐responsive autoimmune hemichorea

Rodin,

Venna,

Balaban

2024

Ann Clin Transl Neurol

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IntroductionSubacute adult‐acquired hemichorea is a striking presentation with a broad differential, including ischemic, metabolic, and inflammatory causes.CaseWe encountered a 74‐year‐old woman with rapid onset of hemichorea and associated encephalopathy. Following a thorough workup without identification of clear imaging or laboratory abnormalities, we empirically treated with IVIg. Her hemichorea dramatically improved. Due to relapses of hemichorea, she required repeat immunotherapy with IVIg or high dose steroids followed by maintenance mycophenolate.DiscussionThis case of seronegative autoimmune hemichorea highlights the importance of a high index of suspicion for an inflammatory etiology of chorea when other causes are ruled out and performing an immunotherapy trial.

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Section: Discussionmentioning

confidence: 99%