Post-laser in situ keratomileusis interface Arthrographis kalrae keratitis

Fernández-Barrientos, Y; Ramos-Suárez, Antonio; Fernández-Sánchez, Fernando; Tirado-Carmona, Antonio

doi:10.5935/0004-2749.20200004

Cited by 3 publications

(1 citation statement)

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“…Many patients with eye defects, including people of all ages, wish to eliminate their visual disorders and stop wearing glasses or contact lenses. At present, laser vision correction (LVC) procedures are considered significantly safer than contact lenses, since the risk of infection during the procedure is lower than while wearing contact lenses for more than a year (0.035% for LVC procedures) [1][2][3]. During the qualifying examination, each patient must be individually considered, given that the selection of an LVC method depends on numerous factors, such as cornea parameters, the severity of the visual defect, the patient's demands and expectations, the patient's profession, and other forms of activity (sport, hobby) [4,5].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Changes in Cap and Residual Stromal Thickness Values during a 6-Month Observation after Refractive Lenticule Extraction Small Incision Lenticule Extraction

Janiszewska-Bil,

Czarnota-Nowakowska,

Kuciel-Polczak

et al. 2024

JCM

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Background: In this study, the changes in corneal cap and residual stromal thickness (RST) values during a 180-day observation period after refractive lenticule extraction small incision lenticule extraction (ReLEx SMILE) were assessed. Methods: Fifty patients underwent ReLEx SMILE using the VisuMax 500 femtosecond laser, with corneal imaging conducted pre and post procedure via anterior segment optical coherence tomography (AS-OCT). Cap thickness in the center and 1.5 mm from the center in four meridians was measured at various intervals. Results: The results showed a significant decrease in cap thickness 180 days post procedure compared to earlier intervals (p < 0.05). Similarly, RST decreased gradually and significantly post procedure (p < 0.05). Notably, changes in cap thickness within the central 1.5 mm area were more dynamic than RST changes during the 6-month observation period following SMILE. Conclusions: The corneal cap thickness measured with swept-source AS-OCT within the central 1.5 mm area underwent more dynamic changes than the residual stromal thickness during the 6-month observation following SMILE.

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Section: Introductionmentioning

confidence: 99%

Assessment of Changes in Cap and Residual Stromal Thickness Values during a 6-Month Observation after Refractive Lenticule Extraction Small Incision Lenticule Extraction

Janiszewska-Bil,

Czarnota-Nowakowska,

Kuciel-Polczak

et al. 2024

JCM

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Arthrographis kalrae Keratitis Complicated by Endophthalmitis: A Case Report With Literature Review

Ting

McKenna

Sadiq

et al. 2020

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

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Objectives: To report the first case of Arthrographis kalrae keratitis complicated by endophthalmitis in the UK and to review the current literature. Methods: A case report with literature review. Results: A 65-year-old male patient, with a background of treated B-cell lymphoma and herpes simplex virus-related neurotrophic keratopathy, presented with a large infiltrative corneal ulcer in the right eye. The patient was immediately commenced on empirical antifungal treatment in view of the clinical suspicion of fungal keratitis (FK). The initial corneal scrape identified the organism as nonspecific “mold,” and the identity of A. kalrae was subsequently confirmed using matrix-assisted laser/desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS). During the clinical course, the patient received topical, intrastromal, intracameral, and systemic antifungal treatment, repeat therapeutic corneal cross-linking treatment, and three penetrating keratoplasties. Although a temporary improvement was achieved with therapeutic corneal cross-linking treatment, the FK progressed relentlessly and was ultimately complicated by an endophthalmitis despite maximum medical and surgical treatment, eventuating in an enucleation. Conclusions: A. kalrae keratitis is an exceptionally rare clinical entity that poses significant therapeutic challenges. MALDI-TOF-MS serves as a useful diagnostic technique in identifying this rare organism. Although the literature suggested that A. kalrae keratitis may sometimes be controlled with antifungal medical treatment alone, this approach was proven to be futile in our immunocompromised patient with pre-existing neurotrophic keratopathy, suggesting that early surgical intervention such as therapeutic keratoplasty may be required in these cases.

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Refractory Post-Operative Wound Infection by Arthrographis Kalrae: A Case Report and Review of Literature

Deshkar,

Patil,

Amberkar

et al. 2024

EJMED

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Arthrographis kalrae (A. Kalrae) infections, although rare, have often demonstrated an extended clinical course. We report a case of refractory post-operative wound infection with A. Kalrae after radical soft tissue and femur resection following total femoral replacement. Identification of A. Kalrae was done based on detailed microscopic and phenotypic characteristics and biochemical tests. Additionally, it was confirmed with sequencing. Although antifungal therapy was started on the basis of the breakpoints observed, clinical failure was met. However, wound infection was subsequently controlled with extensive tissue debridement and a combination of antifungal drug therapy over a period of 33 weeks. The rarity of global data about such unusual fungal infections adds to diagnostic and therapeutic challenges.

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Post-laser in situ keratomileusis interface Arthrographis kalrae keratitis

Cited by 3 publications

References 0 publications

Assessment of Changes in Cap and Residual Stromal Thickness Values during a 6-Month Observation after Refractive Lenticule Extraction Small Incision Lenticule Extraction

Assessment of Changes in Cap and Residual Stromal Thickness Values during a 6-Month Observation after Refractive Lenticule Extraction Small Incision Lenticule Extraction

Arthrographis kalrae Keratitis Complicated by Endophthalmitis: A Case Report With Literature Review

Refractory Post-Operative Wound Infection by Arthrographis Kalrae: A Case Report and Review of Literature

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