Post-fecal microbiota transplant taxa correlate with 3-month survival in severe alcoholic hepatitis patients

Sharma, Shvetank; Pande, Apurva; Khillan, Vikas; Rastogi, Archana; Arora, Vinod; Shasthry, Saggere Muralikrishna; Rajan, Vijayraghavan; Kumar, Guresh; Kumar, M.; Mondot, Stanislas; Doré, Joël; Sarin, Shiv Kumar

doi:10.1016/s0168-8278(20)30785-6

Cited by 4 publications

(2 citation statements)

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“…Butyricicoccus, Bifidobacterium, Lactobacillus, Collinsella, Roseburia, and Dorea, which were absent pre-FMT, were introduced after therapy. The phylum Firmicutes, family Lachnospiraceae, and genera Veillonella and Prevotella are associated with good FMT outcomes (52). Moreover, a recent study showed that, in patients with SAH, healthy donor FMT is associated with significantly less episodes of HE, critical infections, hospitalizations, and alcohol relapse (with a trend toward higher survival rates) than corticosteroid therapy.…”

Section: J O U R N a L P R E -P R O O F 22 / 39mentioning

confidence: 99%

Gut Microbiome and Alcohol-associated Liver Disease

Philips

Schnabl

Bajaj

2022

Journal of Clinical and Experimental Hepatology

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: J O U R N a L P R E -P R O O F 22 / 39mentioning

confidence: 99%

Gut Microbiome and Alcohol-associated Liver Disease

Philips

Schnabl

Bajaj

2022

Journal of Clinical and Experimental Hepatology

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“…In their following studies, they found that bilirubin, Child–Turcotte–Pugh (CTP), and Model for End-Stage Liver Disease (MELD) and MELD-sodium scores decreased significantly in the FMT group compared to the historical controls group [73] . FMT showed a better outcome compared to steroid therapy for 90-day survival in SAH [74] …”

Section: Benefits From Fmtmentioning

confidence: 99%

Encyclopedia of fecal microbiota transplantation: a review of effectiveness in the treatment of 85 diseases

Wang

Zhang

Borody

et al. 2022

Chinese Medical Journal

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Fecal microbiota transplantation (FMT) has been used as a core therapy for treating dysbiosis-related diseases by remodeling gut microbiota. The methodology and technology for improving FMT are stepping forward, mainly including washed microbiota transplantation (WMT), colonic transendoscopic enteral tubing (TET) for microbiota delivery, and purified Firmicutes spores from fecal matter. To improve the understanding of the clinical applications of FMT, we performed a systematic literature review on FMT published from 2011 to 2021. Here, we provided an overview of the reported clinical benefits of FMT, the methodology of processing FMT, the strategy of using FMT, and the regulations on FMT from a global perspective. A total of 782 studies were included for the final analysis. The present review profiled the effectiveness from all clinical FMT uses in 85 specific diseases as eight categories, including infections, gut diseases, microbiota–gut–liver axis, microbiota–gut–brain axis, metabolic diseases, oncology, hematological diseases, and other diseases. Although many further controlled trials will be needed, the dramatic increasing reports have shown the promising future of FMT for dysbiosis-related diseases in the gut or beyond the gut.

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Gut Microbiota-Related Clinical Events and Therapeutic Interventions in Alcohol-Associated Liver Disease

Philips

Arab

et al. 2022

Human Microbiome

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Post-fecal microbiota transplant taxa correlate with 3-month survival in severe alcoholic hepatitis patients

Cited by 4 publications

References 0 publications

Gut Microbiome and Alcohol-associated Liver Disease

Gut Microbiome and Alcohol-associated Liver Disease

Encyclopedia of fecal microbiota transplantation: a review of effectiveness in the treatment of 85 diseases

Gut Microbiota-Related Clinical Events and Therapeutic Interventions in Alcohol-Associated Liver Disease

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