Possible role of polyamines in the function of brown adipose tissue.

Summary The thermogenic response of brown adipocytes to glucagon was reduced by either thyroidectomy or adrenalectomy, while that to noradrenaline was not affected. Polyamines (spermine and spermidine) inhibited glucagon-induced thermogenesis of the cells. These results suggest that glucagon stimulates brown adipocytes under the influence of thyroidal and adrenal hormones, and that polyamines regulate the thermogenesis of brown adipocytes in an inhibitory way.

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Possible role of polyamines in the function of brown adipose tissue.

Abstract: In order to ascertain possible involvement of polyamines in the physiological regulation of brown fat function, effect of temperature amines on the noradrenaline

Cited by 3 publications

References 32 publications

Phenotypic characteristics of adipocyte-like cells generated from C2C12 myoblasts cultured with chicken serum

Phenotypic characteristics of adipocyte-like cells generated from C2C12 myoblasts cultured with chicken serum

Polyamine metabolism in macrophage–adipose tissue function and homeostasis

Influence of endocrine and chemical factors on glucagon-induced thermogenesis in brown adipocytes.

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