Possible mechanism of E. coli messenger rna degradation: non-enzymatic degradation

Accelerated hydrolysis of esters catalyzed by receptors, II. Degradation of RNA by polyvinylpyrrolidone

“…Despite the ever increasing possibility that biological receptors may play important physiological roles of the control of RNA (e.g., mRNA) stability [5,6] via extensive noncovalent interactions with cis-actmg sequoace of the RNA structure having inherent instability [7], little is known about the kinetics and mechanisms of degradative receptor's action on RNA and other phosphodiesters [8].…”