“…Intriguingly, self-domestication and attendant relaxation of selection may also have shaped the recent evolution of our own species' cognition, language capability, development, physiology, and life history (Deacon, 2010;Kuhlwilm & Boeckx, 2018;Theofanopoulou et al, 2017). For example, heritable deleterious traits affecting visual and craniofacial development are more prevalent in civilized populations-suggesting these comparatively enriched environments may buffer purifying selection (Post, 1971). These similarities between humans and other domesticated organisms make our beasts of burden valuable tools for the investigation of recent human evolution, including self-domestication's potential effects on maladaptive human traits such as genetic disease (Boyko, 2011;Johnsson, Williams, Jensen, & Wright, 2016;Persson, Wright, Roth, Batakis, & Jensen, 2016).…”