Possibilities of clinical neuroimaging assessment scales using for patient severity in the onset of cerebral hemorrhagic supratentorial stroke to predict the outcome of the disease acute period

Abstract

The main purpose of the study was to determine the criteria for the vital and functional prognosis of the cerebral hemorrhagic supratentorial stroke (CHSS) acute period outcome based on the Hemphill Intracerebral Hemorrhage (Hemphill-ICH) Scale and ICH-Grading Scale (ICH-GS) in the onset of the disease. Materials and methods. A prospective, cohort, complex clinical and paraclinical study was conducted in 124 patients (72 men and 52 women, mean age 64.7 ± 1.1 years) with CHSS. This study included clinical assessment using National Institute of Health Stroke Scale and Glasgow Coma Scale, visualization of cerebral structures and integrated assessment of health state severity using the Hemphill-ICH Scale and ICH-GS. The functional outcome of the acute period was determined by the modified Rankin Scale. Results. The Hemphill-ICH Scale score ≥2 and ICH-GS score ≥8 are associated with an increased risk of CHSS acute period lethal outcome, at 7.1 [2.8-18.0] (P < 0.01) and 4.4 [2.2-9.3] times (P < 0.01), respectively. The Hemphill-ICH Scale is characterized by a higher informative value for CHSS acute period lethal outcome prediction (AUC = 0.84) in comparison with the ICH-GS (AUC = 0.78, P < 0.05). The ICH-GS is characterized by a higher informative value for the functional prognosis of CHSS acute period outcome (AUC = 0.69) in comparison with the Hemphill-ICH Scale (AUC = 0.61, P < 0.05). Conclusions. Predictors of CHSS acute period lethal outcome are Hemphill-ICH Scale score ≥ 2 and ICH-GS score ≥8. The Hemphill-ICH Scale score = 0 and ICH-GS score = 5 are the criteria for the favourable functional outcome of CHSS acute period (mRS score ≤3 on the 21st day). The informative value of the Hemphill-ICH Scale and ICH-GS is higher for the vital prognosis than for the functional prognosis of CHSS acute period outcome verification.

Possibilities of verification of a short-term functional outcome prognosis in the acute period of spontaneous supratentorial intracerebral hemorrhage using modified variants of the Intracerebral Hemorrhage Scale

“…At the same time, the results of our previous study showed a significantly lower informative value of the oICH Scale when used to evaluate a short-term functional prognosis in this cohort of patients [7]. All of the above justifies the search for alternative tools for clinical neuroimaging scoring.…”