Positron Emission Tomography/Computed Tomography for Diagnosis of Prosthetic Valve Endocarditis

Saby, Ludivine; Laas, Olivia; Habib, Gilbert; Cammilleri, Serge; Mancini, Julien; Tessonnier, L.; Casalta, Jean Paul; Gouriet, Frédérique; Ribéri, Alberto; Avierinos, Jean-François; Collart, Frédéric; Mundler, O.; Raoult, Didier; Thuny, Franck

doi:10.1016/j.jacc.2013.01.092

Cited by 434 publications

(108 citation statements)

References 30 publications

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“…The combination of MSCT with PET has been shown to have an added value over TTE/TEE in confirming PVE,65, 66 especially in patients with negative or doubtful echocardiographic results 67. On the basis of these data, the latest guidelines on the management of IE12 considered an abnormal activity around the site of the prosthetic valve detected on PET/MSCT as a “major criterion” of IE.…”

Section: Discussionmentioning

confidence: 99%

Infective Endocarditis After Melody Valve Implantation in the Pulmonary Position: A Systematic Review

Abdelghani

Nassif

Blom

et al. 2018

JAHA

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BackgroundInfective endocarditis (IE) after transcatheter pulmonary valve implantation (TPVI) in dysfunctioning right ventricular outflow tract conduits has evoked growing concerns. We aimed to investigate the incidence and the natural history of IE after TPVI with the Melody valve through a systematic review of published data.Methods and ResultsPubMed, EMBASE, and Web of Science databases were systematically searched for articles published until March 2017, reporting on IE after TPVI with the Melody valve. Nine studies (including 851 patients and 2060 patient‐years of follow‐up) were included in the analysis of the incidence of IE. The cumulative incidence of IE ranged from 3.2% to 25.0%, whereas the annualized incidence rate ranged from 1.3% to 9.1% per patient‐year. The median (interquartile range) time from TPVI to the onset of IE was 18.0 (9.0–30.4) months (range, 1.0–72.0 months). The most common findings were positive blood culture (93%), fever (89%), and new, significant, and/or progressive right ventricular outflow tract obstruction (79%); vegetations were detectable on echocardiography in only 34% of cases. Of 69 patients with IE after TPVI, 6 (8.7%) died and 35 (52%) underwent surgical and/or transcatheter reintervention. Death or reintervention was more common in patients with new/significant right ventricular outflow tract obstruction (69% versus 33%; P=0.042) and in patients with non‐streptococcal IE (73% versus 30%; P=0.001).ConclusionsThe incidence of IE after implantation of a Melody valve is significant, at least over the first 3 years after TPVI, and varies considerably between the studies. Although surgical/percutaneous reintervention is a common consequence, some patients can be managed medically, especially those with streptococcal infection and no right ventricular outflow tract obstruction.

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Section: Discussionmentioning

confidence: 99%

Infective Endocarditis After Melody Valve Implantation in the Pulmonary Position: A Systematic Review

Abdelghani

Nassif

Blom

et al. 2018

JAHA

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“…Recently, other imaging techniques, such as multislice computed tomography (CT)8, 9, 10 and 18 F‐FDG ( 18 F‐fluorodeoxyglucose) positron emission tomography/CT10, 11, 12 have been shown to be useful particularly in the setting of suspected prosthetic valve IE11 and have been included in the new European Society of Cardiology (ESC) criteria 137 without significantly decreasing their specificity 11.…”

Section: Diagnosing Tavr Endocarditismentioning

confidence: 99%

“…18 F‐FDG positron emission tomography/CT has been shown to increase the sensitivity of the Duke criteria7 without significantly decreasing their specificity 11. However, positron emission tomography/CT has not been specifically studied in suspected TAVR‐IE, the value of cardiac CT is unknown in this setting, and the value of the combination of these techniques in a multimodality approach is unknown 6…”

Section: Diagnosing Tavr Endocarditismentioning

confidence: 99%

Infective Endocarditis After Transcatheter Aortic Valve Replacement: The Worst That Can Happen

Habib

2018

JAHA

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“…Despite the fact that PET with 18FDG has high sensitivity in the diagnosis of inflammation, a number of authors have noted a rather low specificity of the method [79,80,81]. In a study of Rouzet F. et al a comparison of PET-CT with 18FDG and SPECT-CT with 99 mTc-HMPAOlabeled autoleukocytes for diagnoses of endocarditis was performed, and it was shown that the scintigraphy study had a significantly higher diagnostic efficiency compared to PET [82 ].…”

mentioning

confidence: 99%

Modern Opportunities of Radionuclide Methods for Diagnosis of Inflammatory Processes in the Myocardium

Сазонова¹,

Ilyushenkova²,

Lishmanov³

2017

Rejr

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he review is devoted to the radionuclide diagnostics of inflammatory processes in the myocardium. The work briefly describes the main radiopharmaceuticals proposed for visualization of inflammation in cardiology, compares their scintigraphic characteristics, parameters of sensitivity and specificity. The authors discuss unsolved problems, as well as the prospects of nuclear medicine in terms of diagnosing inflammatory diseases. Literature was searched using electronic bibliographic databases, such as Medline, PubMed, E-library.

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Positron Emission Tomography/Computed Tomography for Diagnosis of Prosthetic Valve Endocarditis

Abstract: The use of (18)F-FDG PET/CT was helpful for diagnosing PVE. The results of this study support the addition of abnormal FDG uptake as a novel major criterion for PVE.

Cited by 434 publications

References 30 publications

Infective Endocarditis After Melody Valve Implantation in the Pulmonary Position: A Systematic Review

Infective Endocarditis After Melody Valve Implantation in the Pulmonary Position: A Systematic Review

Infective Endocarditis After Transcatheter Aortic Valve Replacement: The Worst That Can Happen

Modern Opportunities of Radionuclide Methods for Diagnosis of Inflammatory Processes in the Myocardium

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