Positively charged imidazolium‐based ionic liquid‐protected silver nanoparticles: a promising disinfectant in root canal treatment

Abstract

Ag NP surface charge was important in bactericidal efficacy against E. faecalis. The positively charged imidazolium-based ionic liquid-protected Ag NPs showed promising antibacterial results against E. faecalis and exhibited a high level of cytocompatibility to L929 cells.

Antibacterial properties of silver nanoparticles as a root canal irrigant against Enterococcus faecalis biofilm and infected dentinal tubules

“…Biofilms developed in vitro for short periods of time may not have the same resistance as a mature biofilm (Guerreiro-Tanomaru et al 2013). The characteristics of nanoparticles, such as contact time, concentration, particle size and surface charge, influence their antimicrobial action against bacterial cells and mature biofilm (Shrestha et al 2010, Wu et al 2014, Abbaszadegan et al 2015. The 94 ppm silver nanoparticle solution tested was not effective in disrupting E. faecalis biofilm when compared with NaOCl.…”

“…With a focus on their antimicrobial effects, they have been incorporated into bonding agents and restorative materials to prevent biofilm formation and reduce caries (Durner et al 2011, Garcia-Contreras et al 2011, Cheng et al 2012, orthodontic adhesives (Ahn et al 2009, Degrazia et al 2016) and into implant materials (Sheikh et al 2010, Allaker & Memarzadeh 2014. Silver nanoparticles have been tested as endodontic irrigants and intracanal medicaments (Wu et al 2014, Abbaszadegan et al 2015, added to calcium hydroxide as a vehicle (Javidi et al 2014, Afkhami et al 2015, incorporated into endodontic filling materials (Mohamed Hamouda 2012, Correa et al 2015 and calcium silicate cements (Bahador et al 2015, Vazquez-Garcia et al 2016, and have shown lower levels of cytotoxicity (Gomes-Filho et al 2010, Takamiya et al 2016. Silver nanoparticles have been tested as endodontic irrigants and intracanal medicaments (Wu et al 2014, Abbaszadegan et al 2015, added to calcium hydroxide as a vehicle (Javidi et al 2014, Afkhami et al 2015, incorporated into endodontic filling materials (Mohamed Hamouda 2012, Correa et al 2015 and calcium silicate cements (Bahador et al 2015, Vazquez-Garcia et al 2016, and have shown lower levels of cytotoxicity (Gomes-Filho et al 2010, Takamiya et al 2016.…”

“…Nanoparticles have also been studied in the endodontic field in an attempt to reduce E. faecalis adherence to dentine, eliminate biofilms (Kishen et al 2008, Shrestha et al 2010 and enhance root canal disinfection of dentinal tubules (Shrestha et al 2009). Silver nanoparticles have been tested as endodontic irrigants and intracanal medicaments (Wu et al 2014, Abbaszadegan et al 2015, added to calcium hydroxide as a vehicle (Javidi et al 2014, Afkhami et al 2015, incorporated into endodontic filling materials (Mohamed Hamouda 2012, Correa et al 2015 and calcium silicate cements (Bahador et al 2015, Vazquez-Garcia et al 2016, and have shown lower levels of cytotoxicity (Gomes-Filho et al 2010, Takamiya et al 2016.…”

The Effect of Charge at the Surface of Silver Nanoparticles on Antimicrobial Activity against Gram-Positive and Gram-Negative Bacteria: A Preliminary Study

“…This type of AgNPs was synthesized according to the procedure suggested by Abbaszadegan et al [21]. In brief, all laboratory glassware were put in a 1 : 3 of HCl/HNO 3 solution and then rinsed thoroughly three times with triply distilled water.…”

Synthesis and Characterization of New Chlorhexidine-Containing Nanoparticles for Root Canal Disinfection

“…In endodontics, nanoparticles have been suggested to act as irrigants [12], incorporated into intracanal medicaments [13] or root canal sealers [14,15]. Nanoparticle technology for drug delivery includes nanoencapsulation, which is the coating of a substance within another material, typically a polymer based system.…”