Position paper on diagnosis and treatment of atopic dermatitis

Darsow, Ulf; Lübbe, Jann; Taı̈eb, Alain; Seidenari, Stefania; Wollenberg, Andreas; Calza, Anne‐Marie; Giusti, Francesca; Ring, Johannes

doi:10.1111/j.1468-3083.2005.01249.x

Cited by 128 publications

(114 citation statements)

References 78 publications

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“…Successful long-term management of the condition should not only improve the patient’s disease state, but also decrease the amount and/or frequency of treatment needed to maintain control of AD [11]. Pimecrolimus has shown efficacy in AD in various clinical studies [2, 12].…”

Section: Discussionmentioning

confidence: 99%

Steroid-Sparing Effect of Pimecrolimus Cream 1% in Children with Severe Atopic Dermatitis

et al. 2007

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Objective: To investigate if pimecrolimus cream 1% reduces the need for steroids in the long-term management of severe pediatric atopic dermatitis (AD). Methods: A total of 184 pediatric patients (aged 2–17 years) with a history of severe AD according to Rajka and Langeland were enrolled. Patients were randomized to treatment with pimecrolimus cream or vehicle cream for a 24-week period. Prednicarbate 0.25% was applied as rescue medication. Results: Patients on pimecrolimus required steroids on a mean of 29% of study days, compared with 35% of patients on vehicle (p = 0.1841). On the head and neck only, the respective figures were 10 versus 19% (p = 0.0009). In patients enrolled with acute severe disease (Investigator’s Global Assessment ≧4), steroids were used on 28% of the days in the pimecrolimus group compared to 45% in the control group (p = 0.0024). On the head and neck, steroids were used on 10% of study days with pimecrolimus versus 30% with vehicle (p < 0.0001). Conclusion: The results indicate that the need for topical steroids on the head and neck is reduced with pimecrolimus cream 1% in the management of severe pediatric AD according to the definition of Rajka and Langeland.

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Section: Discussionmentioning

confidence: 99%

Steroid-Sparing Effect of Pimecrolimus Cream 1% in Children with Severe Atopic Dermatitis

et al. 2007

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“…Encourage full participation in physical activities when students are well, offer reduced/modified activities if experiencing symptoms. There are many examples of successful education programmes for school children with asthma which incorporate some of the above-mentioned principles (28)(29)(30)(31).…”

Section: Challenges For the Schoolmentioning

confidence: 99%

The management of the allergic child at school: EAACI/GA²LEN Task Force on the allergic child at school

Muraro¹,

Clark

Beyer

et al. 2010

Allergy

118

115

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The management of the allergic child at school: EAACI/GA 2 LEN Task Force on the allergic child at school. Allergy 2010; 65: 681-689. AimThe aim of this Task Force document is to describe an ideal model of care centred on the allergic children at school (Box 1), which is appropriate for use by all stakeholders. Despite a substantial body of literature on allergy management, the evidence available on how to best care for such children at school is inadequate. Furthermore, legislation, education, facilities and health care practices vary between countries. We have presented the information in such a way that individuals will be able to adopt the advice within the context of their local or national facilities to improve care for all children with allergy at school. Where local facilities are not able to support such an approach, this document may be used as a reference to inform national policy. How to use the recommendationsOur key recommendations are presented as 'action points' for schools. Some of these are generic and apply to all allergic children at school (Box 2), and others are presented as disease-specific action points. To facilitate the implementation of these recommendations, specific responsibilities for each stakeholder have been identified (Box 3). A comprehensive protective package for children with allergy at school can therefore be provided within this framework. These recommendations are based upon the available evidence and expert opinion.Allergy at school manifests in multiple ways: eczema, bronchial asthma (hereafter asthma), rhinitis and/or conjunctivitis, food allergy and less commonly venom allergy and AbstractAllergy affects at least one-quarter of European schoolchildren, it reduces quality of life and may impair school performance; there is a risk of severe reactions and, in rare cases, death. Allergy is a multi-system disorder, and children often have several co-existing diseases, i.e. allergic rhinitis, asthma, eczema and food allergy. Severe food allergy reactions may occur for the first time at school, and overall 20% of food allergy reactions occur in schools. Up to two-thirds of schools have at least one child at risk of anaphylaxis but many are poorly prepared. A cooperative partnership between doctors, community and school nurses, school staff, parents and the child is necessary to ensure allergic children are protected. Schools and doctors should adopt a comprehensive approach to allergy training, ensuring that all staff can prevent, recognize and initiate treatment of allergic reactions. urticaria. Children may present with various symptoms such as wheezing and dyspnoea related to asthma, which may be triggered by allergen contact, airway infection or physical exercise. Children with allergic rhinitis (or rhinoconjunctivitis) might have a runny nose, sneeze frequently, mouthbreath persistently and have itchy eyes in spring and/or summer, or they may have all-year-round symptoms. Indoor pollutants can be particularly harmful for students already affected by allergies or asthma...

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“…Özetle, AD'de, SPT, spesifik IgE ve APT sonuçlarının klinik ile ilişkisini belirleyecek ve aeroalerjenlerin rolünü aydınlatabilecek standardize provokasyon testleri bulunmamaktadır. Bu nedenle düşük prediktif değerlerine rağmen günlük pratikte sık kullanılan SPT ve spesifik IgE ile APT sonuçları birlikte değerlendirilmelidir 70,76 .…”

Section: İnhalan/aeroalerjenlerunclassified

The Turkish guideline for the diagnosis and management of atopic dermatitis-2018

Ertam¹,

Küçük²,

Alper³

et al. 2018

TURKDERM

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Position paper on diagnosis and treatment of atopic dermatitis

Cited by 128 publications

References 78 publications

Steroid-Sparing Effect of Pimecrolimus Cream 1% in Children with Severe Atopic Dermatitis

Steroid-Sparing Effect of Pimecrolimus Cream 1% in Children with Severe Atopic Dermatitis

The management of the allergic child at school: EAACI/GA²LEN Task Force on the allergic child at school

The Turkish guideline for the diagnosis and management of atopic dermatitis-2018

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Position paper on diagnosis and treatment of atopic dermatitis

Cited by 128 publications

References 78 publications

Steroid-Sparing Effect of Pimecrolimus Cream 1% in Children with Severe Atopic Dermatitis

Steroid-Sparing Effect of Pimecrolimus Cream 1% in Children with Severe Atopic Dermatitis

The management of the allergic child at school: EAACI/GA2LEN Task Force on the allergic child at school

The Turkish guideline for the diagnosis and management of atopic dermatitis-2018

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Product

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The management of the allergic child at school: EAACI/GA²LEN Task Force on the allergic child at school