POS-215 A case of hemolytic uremic syndrome after mitral valve annuloplasty procedure

Abstract

it possible to determine with high accuracy the threshold values of interstitial fibrosis (>40%) and expression of E-cadherin (<10%) from tubulo-interstitium, in which the achievement of renal response is impossible with a probability close to 80% (Figures 2 and 3). Conclusions: The main characteristic of AKI due to MCN is the rapid (within 2 months) formation of irreversible changes in kidneys: interstitial fibrosis and loss of tubular epithelial phenotype. This is emergency and require intense antimyeloma therapy to achieve hematologic and renal response. The quantitative computer morphometric assessment increases the accuracy of nephropathology studied and can be used in prognostic models.