Porous polymer monolith templated by small polymer molecules

Abstract

Porous poly(ethylene glycol) diacrylate (PEGDA) monoliths have been prepared by UV-initiated polymerization of PEGDA oligomer (M n = 700 g/mol). In the mean time, the addition of hydrophobic poly(propylene oxide) (PPO, M n = 725 g/mol) as porogen into an ethanol solution of PEGDA oligomer to form a homogenous mixture, causes a phase separation between PPO and PEGDA following removal of ethanol by UV heating. Porous PEGDA monolith was prepared by immediate heating at 300 • C to remove PPO molecules from the as-synthesized PEGDA/PPO hybrid. The micrometer pores of the PEGDA monolith have relatively concentrated pore size distribution according to the mercury intrusion porosimetry results and field emission scanning electron microscopy (FE-SEM).On a préparé des monolithes poreux de polyéthylène glycol diacrylate (PEGDA) au moyen de la polymérisation déclenchée par des UV d'oligomère de PEGDA (M n = 700 g/mole). Entre-temps, l'ajout d'oxyde de polypropylène hydrophobe (OPP, M n = 725 g/mole) comme agent porogène dans une solution d'éthanol d'oligomère de PEGDA afin de former un mélange homogène cause une séparation de phases entre l'OPP et le PEGDA après l'élimination de l'éthanol par chauffage aux UV. On a préparé le monolithe poreux de PEGDA en ayant recours au chauffage immédiatà 300 • C afin d'éliminer les molécules d'OPP de l'hybride de PEGDA/OPP synthétisé. Les pores du micromètre du monolithe de PEGDA ont une distribution de la taille des pores relativement concentrée selon les résultats de la porosimétrie de l'intrusion de mercure et de la microscopié electroniqueà balayageàémission de champ (CFE-SEM).

Challenges and strategies in the preparation of large-volume polymer-based monolithic chromatography adsorbents

“…The choice of templates and its method of removal are very important to ensure that the monolith structure remains intake while the template is being removed. Porous poly(ethylene glycol) diacrylate (PEGDA) monoliths have been prepared by the UV‐initiated polymerization of PEGDA oligomer ( M n = 700 g/mol) in ethanol containing hydrophobic poly(propylene oxide) (PPO, M n = 725 g/mol) as the porogen . This reaction causes a phase separation between PPO and PEGDA due to the removal of ethanol by UV heating.…”

“…The choice of pyrolysis temperature is equally vital in this process as PEGDA and PPO have quite similar thermal decomposition temperatures. The micrometer pores of the PEGDA monolith can be characterized as concentrated pore size distribution according to the mercury intrusion porosimetry results and field emission SEM . Unfortunately, this technique is limited by the amount of UV light that can penetrate into the monomeric solution once the polymerization has been initiated.…”

Quest for organic polymer-based monolithic columns affording enhanced efficiency in high performance liquid chromatography separations of small molecules in isocratic mode

“…For example, thermally and photoinitiated free radical polymerization was used to prepare monoliths from methylene-bis-acrylamide [48] and poly(ethylene) diacrylate [49] with poly(ethylene glycol) or poly(propylene glycol) as respective porogens. The authors demonstrated specific morphological features of their monoliths however without showing any chromatographic applications.…”

Poly(ethylene glycol) diacrylate based monolithic capillary columns for the analysis of polar small solutes by capillary electrochromatography

“…One of these smart strategies is based on the use of single cross‐linkers as monomers in the polymerization mixture. In this sense, single monomers based on dimethacrylate , diacrylate , divinylbenzene , N , N ‐methylenebis(acrylamide) , 1,2‐bis( p ‐vinylphenyl)ethane , and tetrakis(4‐vinylbenzyl)silane have been reported. In particular, Lee's group have explored the influence of linking alkyl length in alkylene dimethacrylates on separation performance of monolithic capillary columns reaching column efficiencies of 54 000 plates/m.…”