Porous hydroxyapatite granules: their synthesis, application and characterisation

Zhang, Xingdong; Chen, Jiyong; Zhou, Jiming; Feng, Jianmin; Cheguei, Li; Chen, Anyu; Cen, Yuankun; Wang, Shaoan

doi:10.1016/0267-6605(89)90012-7

Cited by 20 publications

(5 citation statements)

References 4 publications

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“…The mechanical interactions between the rods, and these truncated pyramids lead to the rupture of the rods into small segments, which are then rounded by the rotational movements and the interactions with the truncated pyramids. Since all paste-based methods (i.e., spray granulation, 89 , 90 extrusion-spheronization, 89 , 91 sieve-shaking 92 ) involve fairly viscous pastes, the particles obtained by these methods are typically in the millimeter range.…”

Section: Methods To Produce Spherical Cap Particlesmentioning

confidence: 99%

“…Generally, the liquid amount has to lie just below (spray-granulation, 89 , 90 sieve shaking 92 ) or just above (extrusion-spheronization 89 , 91 ) the plastic limit of the powder (the plastic limit is defined as the minimum amount of water that has to be added to a powder to get a paste). However, the plastic limit may vary and small deviations may provoke drastic changes of the paste viscosity, in particular for powders with a fairly large mean particle size (> 1–10 µm).…”

Section: Methods To Produce Spherical Cap Particlesmentioning

confidence: 99%

“…Even though certain production methods provide particle populations with a narrow size distribution, such populations are generally classified, for example by sieving 90 . This is not only a way to remove too small or too large particles, but also to control their sizes.…”

Section: Consolidation Methodsmentioning

confidence: 99%

“…Unfortunately, the determination of the mechanical properties of spherical particles, particularly of such small diameters, is very difficult and hence hardly performed 90 , 121 . The few attempts of mechanical characterization found in the literature hence still leave room for speculation.…”

Section: Consolidation Methodsmentioning

confidence: 99%

“…So, particles should be big enough to promote an easy blood vessel / bone ingrowth but not too large to keep an acceptable resorption time 133 . Zhang et al 90 tried to estimate the size of the intergranular space based on the size of the spherical particles. They came to the conclusion that values close to 1 to 2mm are ideal for orthopedic and dental applications.…”

Section: Consolidation Methodsmentioning

confidence: 99%

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Synthesis of spherical calcium phosphate particles for dental and orthopedic applications

et al. 2013

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Calcium phosphate materials have been used increasingly in the past 40 years as bone graft substitutes in the dental and orthopedic fields. Accordingly, numerous fabrication methods have been proposed and used. However, the controlled production of spherical calcium phosphate particles remains a challenge. Since such particles are essential for the synthesis of pastes and cements delivered into the host bone by minimally-invasive approaches, the aim of the present document is to review their synthesis and applications. For that purpose, production methods were classified according to the used reagents (solutions, slurries, pastes, powders), dispersion media (gas, liquid, solid), dispersion tools (nozzle, propeller, sieve, mold), particle diameters of the end product (from 10 nm to 10 mm), and calcium phosphate phases. Low-temperature calcium phosphates such as monetite, brushite or octacalcium phosphate, as well as high-temperature calcium phosphates, such as hydroxyapatite, β-tricalcium phosphate or tetracalcium phosphate, were considered. More than a dozen production methods and over hundred scientific publications were discussed.

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Section: Methods To Produce Spherical Cap Particlesmentioning

confidence: 99%

Section: Methods To Produce Spherical Cap Particlesmentioning

confidence: 99%

Section: Consolidation Methodsmentioning

confidence: 99%

Section: Consolidation Methodsmentioning

confidence: 99%

Section: Consolidation Methodsmentioning

confidence: 99%

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Synthesis of spherical calcium phosphate particles for dental and orthopedic applications

et al. 2013

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Amorphous phase formation in plasma-sprayed hydroxyapatite coatings

Gross

Berndt

Herman

1998

J. Biomed. Mater. Res.

202

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The amorphous phase content of air plasma-sprayed hydroxyapatite coatings is dependent upon spraying and deposition conditions. X-ray diffraction and optical microscopy were used to investigate the influence of spray parameters on the formation of the amorphous phase. Results show three factors which most influence the formation of the amorphous phase: dehydroxylation of the molten particle during flight, the cooling rate as it impinges onto the metal substrate, and the substrate temperature. Crystalline regions were identified as unmelted particles and elongated recrystallized areas. Amorphous phase regions vary throughout the coating but are more commonly found at the coating-substrate interface, i.e., the regions decrease toward the surface of the coating. Such an inhomogeneous distribution of phase content is expected to affect the clinical process of bone deposition, and therefore successful implant fixation.

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Biomedical Applications

and¹,

Warner²

2002

Handbook of Porous Solids

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Porous hydroxyapatite granules: their synthesis, application and characterisation

Cited by 20 publications

References 4 publications

Synthesis of spherical calcium phosphate particles for dental and orthopedic applications

Synthesis of spherical calcium phosphate particles for dental and orthopedic applications

Amorphous phase formation in plasma-sprayed hydroxyapatite coatings

Biomedical Applications

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