Porocarcinoma: relato de caso

Abstract

Eccrine porocarcinoma is a rare, malignant neoplasm of eccrine sweat glands. It often occurs in elderly people, mean age of 67.5 years. The clinical features are variable and their localization is not related to sweat-gland concentration, occurring mainly on the feet and legs. Disease diagnosis and treatment should be as early as possible in order to avoid tumor aggressiveness that occurs in 20% of the cases. The authors present a case of extensive porocarcinoma on the thorax of a 71-year-old male patient.. Keywords: Acrospiroma; Carcinoma; Eccrine glands; Sweat gland neoplasms Resumo: O porocarcinoma écrino é uma neoplasia maligna, rara, das glândulas sudoríparas écrinas e, com maior frequência, acomete os indivíduos idosos, com idade média de 67,5 anos. Apresenta manifestações clínicas variadas e sua localização não se correlaciona com a concentração das glândulas sudoríparas, ocorrendo, principalmente, nos pés e pernas. O seu diagnóstico e tratamento devem ser precoces para evitar a agressividade do tumor, que ocorre em 20% dos casos. Os autores relatam o caso de um porocarcinoma extenso no tórax, em paciente do sexo masculino, de 71 anos.

Porocarcinoma; presentation and management, a meta-analysis of 453 cases

“…These includes; ductal differentiation, nests of basaloid cells, squamoid tumor cells, infiltrative spinal cells, cells of acanthotic epidermis, Borst Judasson appearance, ulcerated epithelial tumor, bowenoid porocarcinoma, nests of small atypical cells, clear-cell, high infilterative pattern and hyperchromatic nuclear [7], [13], [26], [62], [72], [103], [102]. Surgery was the main mode of therapy with adjuvant chemoradiotherapy if metastasis and/or recurrence occurred [50], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102], [103], [104]. Metastasis was found in 110 (31%) cases [3], [10], [63], [65], [68], [73], [76], [86].…”

Porocarcinoma ecrino metastásico

“…No existe un tratamiento estándar establecido para el porocarcinoma ecrino, pero debido a la alta recurrencia local, los tumores localizados son tratados frecuentemente con escisión amplia con márgenes libres; se sugieren otros tratamientos como la cirugía de Mohs (14) y la terapia fotodinámica (15) . La quimioterapia y radioterapia son recomendadas en casos de metástasis o recurrencia de la enfermedad; sin embargo, existe poca evidencia de un tratamiento eficaz en estos casos (14) .…”