Porocarcinoma on the Face: A Rare Location. Review of the Literature to Explore Its Biological Behavior

Guerrero-Ramos, Brenda; Domínguez‐Cherit, Judith; Esquivel-Pedraza, Lilly; Saeb‐Lima, Marcela

doi:10.1111/dsu.12126

Cited by 3 publications

(2 citation statements)

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“…EPC may arise de novo or as malignant transformation (30%‐50%) of a preexisting benign poroma after a long latency period 58,68,97 . In addition, the occurrence in predamaged skin (trauma and radiotherapy) was described 82 .…”

Section: Discussionmentioning

confidence: 99%

“…The remaining 116 EPC cases of the head and neck from 90 studies were included in the meta‐analysis. The studies consist of 77 single case reports 7‐14,21,25‐93 and 13 case series with an average of three cases 20,23,24,94‐103 . Additionally, four EPC cases of the University Hospital of the Medical University of Vienna and Evangelical Hospital Vienna could be included in the meta‐analysis.…”

Section: Methodsmentioning

confidence: 99%

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Eccrine porocarcinoma of the head and neck: Meta‐analysis of 120 cases

Janik

Liu

et al. 2020

Head & Neck

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Background The aim of the study is to analyze potential prognostic factors and to evaluate therapy strategies regarding clinical outcome in patients with eccrine porocarcinoma (EPC) of the head and neck. Methods One hundred and sixteen EPC cases from ninety studies and four authors' EPC cases were included in the meta‐analysis. Results At an average follow up of 20.48 months, the 3‐year overall survival and regional recurrence rate were 70.3% and 19.0%, respectively. Patients without surgical treatment had a significantly worse 3‐year overall survival. Mohs microscopic surgery led to significantly less occurrence of regional recurrences compared to wide excision. An ulcerating lesion, high mitotic activity, and lymphovascular invasion were significant prognostic factors. Conclusion Surgical resection is the cornerstone in the therapy of EPC and represents the therapeutic modality that offers the best chance of disease‐free survival. Due to the high probability of recurrence, close follow‐ups are strongly recommended.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%