Pore structure of gel chitosan membranes. II. Modelling of the pore size distribution from solute diffusion measurements. Gaussian distribution—Mathematical limitations

Krajewska, Barbara; Olech, Andrzej

doi:10.1016/0966-7822(95)00016-x

Cited by 8 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The contribution of diffusion mechanisms to the control of applications involving chitosan‐based materials can be explained by the poor porosity of the raw material 17–20. For this reason, a major challenge in recent decades has been the conditioning of chitosan in the form of gels to alleviate the impact of porosity limitations.…”

Section: Introductionmentioning

confidence: 99%

Diffusion of biological molecules through hollow chitosan fibers

Peirano

Vincent

Guibal

2007

J of Applied Polymer Sci

View full text Add to dashboard Cite

Hollow chitosan fibers were tested for the diffusion of a series of biological macromolecules, including amino acids, vitamins, and antibiotics. The hollow fibers were immersed in the permeant solution, and water was circulated and recycled inside the lumen of the fiber. The concentration of the permeant in the hollow fiber loop was analyzed online by ultraviolet-visible spectrophotometry. The effect of process parameters such as the concentration, pH, and flow rate was tested. The permeability coefficient was calculated from the permeability. The limited influence of the flow rate indicated that resistance to film diffusion (at the surface of the fiber) was not the ratelimiting step: the limiting step remained diffusion through the membrane. The pH would be expected to influence the protonation of chitosan amine groups and the acidbase properties of the permeant; however, the diffusion profiles were little affected by this parameter. The impact of pH on the permeability coefficient decreased in the following order: tryptophan > chloramphenicol > vitamin B12. The change in the concentration of the permeant had a limited impact on the permeability coefficient.

show abstract

Section: Introductionmentioning

confidence: 99%

Diffusion of biological molecules through hollow chitosan fibers

Peirano

Vincent

Guibal

2007

J of Applied Polymer Sci

View full text Add to dashboard Cite

show abstract

“…In the same case, the molecular permeability of the membrane depends on the properties of the permeating reagent. The small molecules are easily transported through the membranes, whereas the large molecules move more slowly or cannot be transported on the basis of the theory of the capillary pore model ( − ).…”

Section: Introductionmentioning

confidence: 99%

Molecular Affinity and Permeability of Different Molecular Weight Chitosan Membranes

Chen

Zheng

Wang

et al. 2002

J. Agric. Food Chem.

View full text Add to dashboard Cite

Membranes were prepared from chitosan with different molecular weights by a casting method. The molecular affinity and permeability of the membranes for sodium chloride, glucose, tyrosine, and bovine serum protein were measured at 4 degrees C and pH 7. The molecular permeability of the chitosan membranes was inversely related to molecular weight. All prepared membranes showed a molecular affinity to bovine serum protein. The higher the molecular weight of chitosan membrane, the higher the affinity and the lower permeability of the membrane to bovine serum protein.

show abstract

“…The pore structure of the membranes was characterized and compared with that of a commercial Cuprophan membrane 17. 29, 30 In this work the effects of glutaraldehyde crosslinking and protein coating on the diffusion properties of chitosan membranes were determined separately. Additionally, after all the diffusion measurements had been completed, the crosslinked and BSA‐coated membranes were stored for 3 months in water at 4 °C, and their diffusion properties were checked again.…”

Section: Introductionmentioning

confidence: 99%

Diffusional properties of chitosan hydrogel membranes

Krajewska

2001

J of Chemical Tech & Biotech

Self Cite

View full text Add to dashboard Cite

Chitosan membranes were prepared by a solvent evaporation technique, followed by crosslinking with glutaraldehyde and coating with BSA. The effects of crosslinking and BSA coating on the pore structure of such prepared hydrogel chitosan membranes were determined. The diffusion rates of 12 non-electrolytes ranging in molecular radius between 2.5 and 14 A Ê through the membranes were measured, and the results were interpreted in terms of the capillary pore model and free volume model of solute diffusional transport through hydrogel membranes. Glutaraldehyde crosslinking was found to reduce the membrane water content and consequently the membrane pore size and surface porosity, whereas further BSA coating brought about the opposite effect. The latter effect lessened with an increase in glutaraldehyde pretreatment of the membranes. The optimal chitosan membrane preparation, compromising between the solute¯ux and membrane stability and durability was obtained when the membranes were crosslinked with glutaraldehyde at concentrations between 0.01 and 0.1% (w/w). The knowledge of transport properties and of physical strength of the membranes is of importance for the development of chitosan-based controlled release systems.

show abstract

Pore structure of gel chitosan membranes. II. Modelling of the pore size distribution from solute diffusion measurements. Gaussian distribution—Mathematical limitations

Cited by 8 publications

References 13 publications

Diffusion of biological molecules through hollow chitosan fibers

Diffusion of biological molecules through hollow chitosan fibers

Molecular Affinity and Permeability of Different Molecular Weight Chitosan Membranes

Diffusional properties of chitosan hydrogel membranes

Contact Info

Product

Resources

About