Porcine Reproductive and Respiratory Syndrome in Hybrid Wild Boars, China

Wu, Jiaqiang; Liu, Shaoning; Zhou, Shun; Wang, Zhao; Li, Kun; Zhang, Yuyu; Yu, Jiang; Xu, Cong; Chi, Xiaowei; Li, Jun; Xu, Shaojian; Du, Yijun; Ren, Sufang; Wang, Jinbao

doi:10.3201/eid/1706.101518

Cited by 15 publications

(10 citation statements)

References 10 publications

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“…In fact, similar observations have been recently observed in the Netherlands when comparing the prevalence of Mycoplasma hyopneumoniae in hybrids which was higher than in pure wild boars [40]. Similarly, in China, hybrids reared in captivity showed higher prevalences of porcine reproductive respiratory syndrome (PRRS) than domestic pigs reared in similar conditions [41]. Considering that wild boar hybrids are quite widespread in many countries worldwide, their potentially distinct epidemiological role in the dissemination of pathogens between domestic pigs and wild boars deserves further investigation.…”

Section: Discussionsupporting

confidence: 63%

Assessment of Domestic Pigs, Wild Boars and Feral Hybrid Pigs as Reservoirs of Hepatitis E Virus in Corsica, France

Jori

Laval

Maestrini

et al. 2016

Viruses

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In Corsica, extensive pig breeding systems allow frequent interactions between wild boars and domestic pigs, which are suspected to act as reservoirs of several zoonotic diseases including hepatitis E virus (HEV). In this context, 370 sera and 166 liver samples were collected from phenotypically characterized as pure or hybrid wild boars, between 2009 and 2012. In addition, serum and liver from 208 domestic pigs belonging to 30 farms were collected at the abattoir during the end of 2013. Anti-HEV antibodies were detected in 26% (21%–31.6%) of the pure wild boar, 43.5% (31%–56.7%) of hybrid wild boar and 88% (82.6%–91.9%) of the domestic pig sera. In addition, HEV RNA was detected in five wild boars, three hybrid wild boars and two domestic pig livers tested. Our findings provide evidence that both domestic pig and wild boar (pure and hybrid) act as reservoirs of HEV in Corsica, representing an important zoonotic risk for Corsican hunters and farmers but also for the large population of consumers of raw pig liver specialties produced in Corsica. In addition, hybrid wild boars seem to play an important ecological role in the dissemination of HEV between domestic pig and wild boar populations, unnoticed to date, that deserves further investigation.

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Section: Discussionsupporting

confidence: 63%

Assessment of Domestic Pigs, Wild Boars and Feral Hybrid Pigs as Reservoirs of Hepatitis E Virus in Corsica, France

Jori

Laval

Maestrini

et al. 2016

Viruses

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“…A potential impact of reported sexual interactions is the possible increase of a hybrid pig population which roams free in the Corsican ecosystem interacting with domestic pigs and pure wild boar populations. Although insufficiently studied, these hybrids are suspected to have distinct reproductive, behavioral, and genetic patterns than pure wild boars that could make them exposed to higher disease burdens than those observed in pure wild boar populations ( 5 , 47 , 48 ). Considering the abundance and distribution of hybrid feral populations in Corsica, and the role they seem to play in similar settings ( 43 ), their potential epidemiological role in disease spread and maintenance deserves further investigation.…”

Section: Discussionmentioning

confidence: 99%

Questionnaire-Based Assessment of Wild Boar/Domestic Pig Interactions and Implications for Disease Risk Management in Corsica

et al. 2017

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Wild boars and domestic pigs belong to the same species (Sus scrofa). When sympatric populations of wild boars, feral pigs, and domestic pigs share the same environment, interactions between domestic and wild suids (IDWS) are suspected to facilitate the spread and maintenance of several pig pathogens which can impact on public health and pig production. However, information on the nature and factors facilitating those IDWS are rarely described in the literature. In order to understand the occurrence, nature, and the factors facilitating IDWS, a total of 85 semi-structured interviews were implemented face to face among 25 strict farmers, 20 strict hunters, and 40 hunting farmers in the main traditional pig-farming regions of Corsica, where IDWS are suspected to be common and widespread. Different forms of IDWS were described: those linked with sexual attraction of wild boars by domestic sows (including sexual interactions and fights between wild and domestic boars) were most frequently reported (by 61 and 44% of the respondents, respectively) in the autumn months and early winter. Foraging around common food or water was equally frequent (reported by 60% of the respondents) but spread all along the year except in winter. Spatially, IDWS were more frequent in higher altitude pastures were pig herds remain unattended during summer and autumn months with limited human presence. Abandonment of carcasses and carcass offal in the forest were equally frequent and efficient form of IDWS reported by 70% of the respondents. Certain traditional practices already implemented by hunters and farmers had the potential to mitigate IDWS in the local context. This study provided quantitative evidence of the nature of different IDWS in the context of extensive commercial outdoor pig farming in Corsica and identified their spatial and temporal trends. The identification of those trends is useful to target suitable times and locations to develop further ecological investigations of IDWS at a finer scale in order to better understand diseases transmission patterns between populations and promote adapted management strategies.

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“…The virulence of SX-1 is high in pigs, as verified by animal infection experiments 29 . The ZCYZ strain with a 54aa deletion in Nsp2 was isolated from hybrid wild boars in 2009 30 . The virulences of the SX-1, ZCYZ, and SD1 strains are high, moderate, and mild, respectively, in pigs, as verified by animal infection experiments 29 – 31 .…”

Section: Methodsmentioning

confidence: 99%

“…SX-1 was a highly virulent strain which characterized with a 30aa deletion in nonstructural protein 2 (Nsp2) and isolated from domestic pigs in 2008 29 . The moderate virulent ZCYZ strain with a 54aa deletion in Nsp2 was isolated from hybrid wild boars in 2009 30 . The SD1 strain was a classic PRRSV strain with no deletion in Nsp2 which was mild virulent to pigs and isolated from domestic pigs in 2004 31 .…”

Section: Introductionmentioning

confidence: 99%

Porcine Reproductive and Respiratory Syndrome Virus strains with Higher Virulence Cause Marked Protein Profile Changes in MARC-145 Cells

Chen

Liu²,

Zhang

et al. 2018

Sci Rep

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Porcine reproductive and respiratory syndrome is an infectious disease that causes serious economic losses to the swine industry worldwide. To better understand the pathogenesis of the porcine reproductive and respiratory syndrome virus (PRRSV), three PRRSV strains with different molecular markers and virulence were used to infect MARC-145 cells. A total of 1804 proteins were identified, and 233 altered proteins and 72 signaling pathways involved in the proteomic profiling of virus-infected MARC-145 cells increased with the virulence of the PRRSV strain. The three types of viral strains shared a common pathway—the electron transport reaction in mitochondria—in the infected-MARC-145 cells. Moreover, the antisense pathway was the most variable of all significant signaling pathways for the highly virulent SX-1 strain, indicating that this unique pathway may be connected to the high virulence of the SX-1 strain. Our study is the first attempt to provide a proteome profile of MARC-145 cells infected with PRRSV strains with different virulence, and these findings will facilitate a deep understanding of the interactions between this virus and its host.

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Porcine Reproductive and Respiratory Syndrome in Hybrid Wild Boars, China

Cited by 15 publications

References 10 publications

Assessment of Domestic Pigs, Wild Boars and Feral Hybrid Pigs as Reservoirs of Hepatitis E Virus in Corsica, France

Assessment of Domestic Pigs, Wild Boars and Feral Hybrid Pigs as Reservoirs of Hepatitis E Virus in Corsica, France

Questionnaire-Based Assessment of Wild Boar/Domestic Pig Interactions and Implications for Disease Risk Management in Corsica

Porcine Reproductive and Respiratory Syndrome Virus strains with Higher Virulence Cause Marked Protein Profile Changes in MARC-145 Cells

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