Populationsgenetische Untersuchung der Esterase D im Lübecker Raum

Abstract

1251 blood samples of non-related human beings coming from the area of Lübeck have been examined. Frequencies of the esterase D allel were EsD1 = 0.9001 and EsD2 = 0.0999.

Human Red Cell Esterase D Polymorphism in Denmark, Its Use in Paternity Cases and the Description of a New Phenotype

“…1976;PJlughaupt et al, 1976;Bargagna et al, 1975;Cortivo et al, 1978;Ranzani et al, 1978]. The frequency of the EsD2 gene in the Danish sample (0.0992) is among the lowest reported for European populations [ Weismann et al, 1979]. The distribution of phenotypes in 1,111 mother/child pairs and in 59 families in cluding 157 children was determined (tables II, III).…”

“…A striking var iation was revealed of the frequencies of the two common alleles (EsD1 and EsD2) between different populations. The high est frequencies of the EsD2-gene were ob served in East-Asian populations [Cart wright et al, 1976;Ebeli-Struijk et al, 1976;Papiha and Nahar, 1977;Weismann et al, 1979], Several rare alleles were detected: EsD3 [Bender and Frank. 1974], EsD3N [Omoto et al, 1978], EsD3 1 [Suzuki et al, 1978], EsD4 [Berget al, 1976], EsDMa [Hitzeroth etal., 1976], EsD6[Rai7nwet al, 1980, and null alleles, EsD0 [Marks et al, 1977;Sparkes et al, 1979;Patschneider and Dirnhofer, 1979;Koziol and Stepien.…”