Population Genomics of Speciation and Admixture

Nadeau, Nicola J.; Kawakami, Takeshi

doi:10.1007/13836_2018_24

Cited by 9 publications

(14 citation statements)

References 190 publications

(217 reference statements)

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“…Naturally occurring hybrid zones have long been used as 'natural laboratories' to study the speciation process [74]. The field of speciation genomics works to understand how genomic differences build up to cause eventual reproductive isolation [75][76][77][78]. Recently, population geneticists have used genome wide markers to ask questions regarding the genomic architecture of reproductive isolation and speciation, and how the genomes of diverged populations change in the face of on-going gene flow [43,78,79].…”

Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

“…The field of speciation genomics works to understand how genomic differences build up to cause eventual reproductive isolation [75][76][77][78]. Recently, population geneticists have used genome wide markers to ask questions regarding the genomic architecture of reproductive isolation and speciation, and how the genomes of diverged populations change in the face of on-going gene flow [43,78,79]. Further, many studies of natural hybrid zones have focused on isolating signals from historical vs. contemporary hybridization (main text 2.1.1, [78]).…”

Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

“…Recently, population geneticists have used genome wide markers to ask questions regarding the genomic architecture of reproductive isolation and speciation, and how the genomes of diverged populations change in the face of on-going gene flow [43,78,79]. Further, many studies of natural hybrid zones have focused on isolating signals from historical vs. contemporary hybridization (main text 2.1.1, [78]). These questions that speciation biologists ask using hybrid zones could equally be asked in anthropogenic hybrid zones, particularly in studies that used whole genome sequence data.…”

Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

“…These questions that speciation biologists ask using hybrid zones could equally be asked in anthropogenic hybrid zones, particularly in studies that used whole genome sequence data. Indeed, studies of anthropogenic hybrid zones may even have more power than those with naturally occurring secondary contact as in some cases of introduced or escaped heterospecifics, phenotypic divergence is more extreme, meaning that fewer individuals would need to be sampled for, for example, admixture mapping [78].…”

Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

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Detecting the True Extent of Introgression during Anthropogenic Hybridization

McFarlane

Pemberton

2019

Trends in Ecology & Evolution

105

178

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Hybridization among naturally separate taxa is increasing due to human impact, and can result in taxon loss. Previous classification of anthropogenic hybridization has largely ignored the case of bimodal hybrid zones, in which hybrids commonly mate with parental species resulting in many backcrossed individuals with a small proportion of introgressed genome. Genetic markers can be used to detect such hybrids, but until recently too few markers have been used to detect the true extent of introgression. Recent studies of wolves and trout have used thousands of markers to reveal previously undetectable backcrosses. This improved resolution will lead to increased detection of late generation backcrosses, shed light on the consequences of anthropogenic hybridization, and pose new management issues for conservation scientists.

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Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

Section: Box 3: Lessons From Natural Systemsmentioning

confidence: 99%

See 2 more Smart Citations

Detecting the True Extent of Introgression during Anthropogenic Hybridization

McFarlane

Pemberton

2019

Trends in Ecology & Evolution

105

178

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“…Individual genes and potentially larger genomic blocks can vary in their contribution to these phenomena, and hence will vary in their propensity for introgression and degree of divergence. Those regions that remain compatible are able to introgress, potentially counteracting divergence by selection and drift (Mallet et al, 2007;Martin and Jiggins, 2017;Nadeau and Kawakami, 2018), whereas selection on regions associated with disrupted expression or phenotypes in hybrids will contribute to maintain or foster divergence.…”

Section: Introductionmentioning

confidence: 99%

Patterns of regulatory divergence and gene expression in hybrids are associated with molecular evolution in species undergoing gene flow

Dı́az

Wolf

Brito

2021

Preprint

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The extent to which hybridization disrupts a gene’s pattern of expression likely governs its propensity for introgression, while its extent of molecular divergence can itself underlie such disruption. Together, these phenomena shape the landscape of sequence and transcriptional divergence across the genome as species diverge. To understand this process, we examine gene expression inheritance, regulatory and molecular divergences in the reproductive transcriptomes of species linked by gene flow. The fruit flies Anastrepha fraterculus and A. obliqua show evidence of gene flow despite clear evolutionary divergence and incomplete reproductive isolation. We find that their transcriptional patterns are a mosaic between those typically observed within and between allopatric species. Genes showing transgressive expression in hybrids or cis-regulatory divergence between species are associated with greater molecular divergence. This may reflect pleiotropic constraints that make them more resistant to gene flow or they may be more likely to experience divergent selection. However, while these highly divergent genes are likely to be important contributors to species differences, they are relatively rare. Instead, most differentially regulated genes, including those linked to reproduction, show high degrees of dominance in hybrids and trans-regulated divergence between species, suggesting widespread genetic compatibility that allowed for the identified introgression. These findings provide insights into how postzygotic isolating mechanisms might evolve in the presence of gene flow: regions showing cis-regulatory divergence or transgressive expression contribute to reproductive isolation, while regions with dominant expression and trans-regulatory divergence act as a buffer of hybrid breakdown, facilitating introgression, and leading to a genomic mosaic of expression and sequence divergence.

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