Population genetics for 17 Y-STR loci in Korean ethnic minority from Liaoning Province, Northeast China

Guo, Fei; Song, Liu; Zhang, Longnian

doi:10.1016/j.fsigen.2016.01.007

Cited by 12 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have explored the relationship between other Han populations (Fan, Zhang, et al, ; Kim, Han, Kim, & Kim, ; Li, Yu, Li, Jin, & Yan, ; Nothnagel et al, ; Sun et al, ; Wang et al, , ; Xu et al, ; Yanmei et al, ; Zhang et al, ; Zhou, Ren, Zhang, Wang, & Huang, ; Zhou et al, ) from the east to the west and from the north to the south among Han ethnic groups. We have also compared Hans of Dalian city to other regional ethnic groups (Adnan, Kasim, et al, ; Bai, Liu, Lv, Shi, & Ma, ; Bian et al, ; Chen et al, ; Du et al, ; Fan et al, ; Fan, Wang, Chen, Long, et al, ; Fan, Wang, Chen, Zhang, et al, ; Gayden, Bukhari, Chennakrishnaiah, Stojkovic, & Herrera, ; Guo, ; Guo, Song, & Zhang, ; Guo, Zhang, & Jiang, ; He & Guo, ; Ji et al, ; Ou et al, ; Shan et al, ; Shi, Bai, Bai, & Yu, ; Song et al, ; Wang et al, ; Yao et al, ; Zhu et al, ) from East Asia and the world.…”

Section: Introductionmentioning

confidence: 99%

RETRACTED: Comprehensive genetic structure analysis of Han population from Dalian City revealed by 20 Y‐STRs

Adnan

Kasimu

Rakha

et al. 2020

Molec Gen & Gen Med

View full text Add to dashboard Cite

Background Dalian is a city formed in the 1880s in Liaoning province, Northeastern China with a population of 6.69 million now. Han is the largest ethnic group not only across Mainland China (92%) and Taiwan (97%) but also considered to be the largest ethnic group of the world contributing to above 18% of world's population. Methods In the current study, we genotyped Goldeneye® 20Y System loci in 879 unrelated male individuals from the Han ethnic group in Dalian city and calculated the forensic parameters of the 20 Y‐STR loci. Results In total, we observed 855 haplotypes, among which 835 (94.99%) were unique. The discrimination capacity (DC) of overall Goldeneye® 20Y System is 97.27% and it slightly reduces to 96.93% when only Y‐filer® set of 17 Y‐STRs were used, which mitigates using the extended set of markers in this population. We found DYS388 showed the lowest gene diversity (0.5151), whereas DYS389II showed the highest gene diversity (0.7621) in single copy Y‐STR, and DYS385 showed the highest gene diversity (0.9683) among all. Conclusion Multidimensional scaling (MDS) analysis based upon pairwise Rst genetic distance showed difference among Han population from the east to the west and from the north to the south. We also predicted haplogroups using Y‐STR haplotypes, which showed the dominance of Haplogroup O (65.2%) followed by Haplogroup C (14.5%) in Dalian Han population. Moreover, we found 10 individuals showed a null allele at the DYS448 in our samples. We also performed linear discriminatory analysis (LDA) between Han and other prominent Chinese minority ethnic groups. We presented Y‐STRs data in the Y‐Chromosome Haplotype Reference Database (YHRD) for the future forensic and other usage.

show abstract

Section: Introductionmentioning

confidence: 99%

RETRACTED: Comprehensive genetic structure analysis of Han population from Dalian City revealed by 20 Y‐STRs

Adnan

Kasimu

Rakha

et al. 2020

Molec Gen & Gen Med

View full text Add to dashboard Cite

show abstract

“…Furthermore, in order to comprehensively investigate the genetic substructure of Liaoning Han population, the population comparison using the 16 shared Y-STR loci except for DYS627, DYS460, DYS518, DYS449, DYF387S1, DYS481, DYS533, DYS576 and DYS570 was performed between Liaoning Han and 22 East Asian groups. They included Anhui Han Chinese [ 25 ], Beijing Han Chinese [ 26 ], Guangdong Han Chinese [ 27 ], Guizhou Han Chinese (YP001096), Jiangsu Han Chinese [ 25 ], Jiangxi Han Chinese [ 25 ], Jilin Han Chinese [ 28 ], Shandong Han Chinese [ 29 ], Shanxi Han Chinese [ 30 ], Yunnan Bai (YP000902), Xishuangbanna Dai (YP000903), Liaoning Hui (YP000819), Liaoning Korean [ 31 ], Liaoning Manchu [ 16 ], Hunan Miao (YP001038), Liaoning Mongolian [ 32 ], Gansu Tibetan (YP001032), Hunan Tujia (YP001037), Liaoning Xibe [ 33 ], Guangxi Zhuang (YP000591), Japanese [ 34 ] and Korean [ 35 ]. Rst values for genetic distance demonstrated that haplotypes of the Liaoning Han population were significantly different from those of the other 22 populations (all p values < 0.05/22 after Bonferroni correction; Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

Genetic Variation of 25 Y-Chromosomal and 15 Autosomal STR Loci in the Han Chinese Population of Liaoning Province, Northeast China

Yao

Wang

2016

PLoS ONE

View full text Add to dashboard Cite

In the present study, we investigated the genetic characteristics of 25 Y-chromosomal and 15 autosomal short tandem repeat (STR) loci in 305 unrelated Han Chinese male individuals from Liaoning Province using AmpFISTR® Yfiler® Plus and IdentifilerTM PCR amplification kits. Population comparison was performed between Liaoning Han population and different ethnic groups to better understand the genetic background of the Liaoning Han population. For Y-STR loci, the overall haplotype diversity was 0.9997 and the discrimination capacity was 0.9607. Gene diversity values ranged from 0.4525 (DYS391) to 0.9617 (DYS385). Rst and two multi-dimensional scaling plots showed that minor differences were observed when the Liaoning Han population was compared to the Jilin Han Chinese, Beijing Han Chinese, Liaoning Manchu, Liaoning Mongolian, Liaoning Xibe, Shandong Han Chinese, Jiangsu Han Chinese, Anhui Han Chinese, Guizhou Han Chinese and Liaoning Hui populations; by contrast, major differences were observed when the Shanxi Han Chinese, Yunnan Bai, Jiangxi Han Chinese, Guangdong Han Chinese, Liaoning Korean, Hunan Tujia, Guangxi Zhuang, Gansu Tibetan, Xishuangbanna Dai, South Korean, Japanese and Hunan Miao populations. For autosomal STR loci, DP ranged from 0.9621 (D2S1338) to 0.8177 (TPOX), with PE distributing from 0.7521 (D18S51) to 0.2988 (TH01). A population comparison was performed and no statistically significant differences were detected at any STR loci between Liaoning Han, China Dong, and Shaanxi Han populations. The results showed that the 25 Y-STR and 15 autosomal STR loci in the Liaoning Han population were valuable for forensic applications and human genetics, and Liaoning Han was an independent endogenous ethnicity with a unique subpopulation structure.

show abstract

“…To study the genetic relationships in the Yanbian Korean population, the genotypes of the sample set were used to calculate the Rst values for the Yanbian Koreans. Then the MDS analysis was performed among the Yanbian Korean population and 26 other reference populations (Guo, 2015;Guo, Song, & Zhang, 2016;Han et al, 2016;Kayser et al, 1997;Kim, Han, Kim, & Kim, 2010;Kwak et al, 2005;Lee et al, 2007;Li, Yu, Li, Jin, & Yan, 2016;Mizuno et al, 2008;Nothnagel et al, 2017;Ou et al, 2015;Park et al, 2005;Seong et al, 2011;Zhang et al, 2014;Zhou et al, 2018;Zhu et al, 2005) from East Asia based on Rst values (Supplementary Table S3; Figure 2). Yanbian Korean population was located closest to previously studied Koreans living in Liaoning province of China (Rst 0.0013), Koreans from Yanbian, China (Rst 0.0021), Koreans from Seoul, South Korea (Rst 0.0042), and Koreans from Chungcheong, South Korea (Rst 0.0047), also appeared to be clustered with the Yanbian Korean population.…”

Section: Population Comparison With Other Populationsmentioning

confidence: 99%

Population genetics of 19 Y‐STR loci in Yanbian Korean samples from China

Xuan

Adnan

Khan

et al. 2018

Annals of Human Genetics

View full text Add to dashboard Cite

Background: China harbors 56 ethnic groups, including Korean, with a population size of approximately 1.92 million at the 2010 census. Most of the Koreans live in Northeastern parts of China, including Jilin (59.64%), Heilongjiang (20.21%), and Liaoning (12.55%) provinces, and the rest are spread to other parts of China. Koreans across China share a common culture, which is similar to Korea. Methods: We have explored the genetic characteristics of 20 Y-chromosomal short tandem repeat (Y-STR) loci in 252 unrelated Chinese Korean male individuals from Jilin Province, using a Goldeneye 20Y amplification kit. Moreover, phylogenetic analysis was performed between the Korean population and other relevant populations based on the Y-STR haplotypes. Results: We have found 237 different haplotypes among 252 unrelated individuals. The haplotype frequencies ranged from 0.0238 to 0.0040, while gene diversity ranged from 0.9666 (DYS385a/b) to 0.2260 (DYS391). The random match probability was 0.0048, the haplotype diversity was 0.9992 ± 0.0006 and discrimination capacity was 0.9405. Population comparison revealed that Korean populations are lining up together with other Korean populations from East Asia. Conclusion: Our results showed that the 20 Y-STR loci in the Yanbian Korean population are valuable for forensic application and human genetics. The Yanbian Koreans have lined up with other Korean population from China and Korea while showing significant differences from other East Asian populations. K E Y W O R D S Goldeneye 20Y kit, Haplotype, Korean population, Y-STR 134

show abstract

Population genetics for 17 Y-STR loci in Korean ethnic minority from Liaoning Province, Northeast China

Cited by 12 publications

References 10 publications

RETRACTED: Comprehensive genetic structure analysis of Han population from Dalian City revealed by 20 Y‐STRs

RETRACTED: Comprehensive genetic structure analysis of Han population from Dalian City revealed by 20 Y‐STRs

Genetic Variation of 25 Y-Chromosomal and 15 Autosomal STR Loci in the Han Chinese Population of Liaoning Province, Northeast China

Population genetics of 19 Y‐STR loci in Yanbian Korean samples from China

Contact Info

Product

Resources

About