Population genetic analysis of 15 autosomal STRs loci in the central region of Argentina

Admixture and genetic relationships of Mexican Mestizos regarding Latin American and Caribbean populations based on 13 CODIS-STRs

“…It is important to note that the focus of this study is the Mexican Mestizo population, and not an analysis of the particular genetic admixture, relationships or structure in Latin American and Caribbean populations. In fact, this analysis is not possible because in most of the cases we included only one population from these countries; however, these issues have been addressed in previous studies (Corach et al, 2010;de Assis Poiares et al, 2010;Marino et al, 2006;Rojas et al, 2010;Wang et al, 2008). Another essential issue is the forensic origin of a large number of population samples, because these commonly include both resident and native individuals from the populations that they represent.…”

“…The admixture analysis in Latin America shows a complex genetic structure and high variation of the Amerindian and European components, principally. These studies have included genome-wide SNPs (Silva-Zolezzi et al, 2009;Bryc et al, 2010) and autosomal STRs in different Latin American populations (Godinho et al, 2008;Marino et al, 2006Wang et al, 2008, and particularly CODIS-STRs in Mexican populations (Rubi-Castellanos et al, 2009a). However, during the last years further STR datasets used in forensic casework have been reported in Mexican-Mestizo populations (Table 1), and the current inter-populational analyses have not included the continental context.…”

Inferring Continental Ancestry of Argentineans from Autosomal, Y‐Chromosomal and Mitochondrial DNA

“…Molecular genetics offers suitable tools to investigate bio‐geographic ancestry in detail including the detection and quantification of admixture proportions. Some information has been published about the genetic make‐up of Argentineans either employing markers from autosomal DNA (Sala et al, 1998, 1999; Marino et al, 2006a,b,c; Seldin et al, 2007), from the non‐recombining part of the Y‐chromosome (NRY) (Kayser et al, 1997; Corach et al, 2001; Kayser et al, 2001; Marino et al, 2007), or, to a lesser degree, also from mitochondrial DNA (mtDNA) (Ginther et al, 1993; Corach et al, 1997; Bobillo et al, 2009), but reliable inferences on bio‐geographic ancestry are limited. Also, the combined analysis of uni‐parentally and bi ‐ parentally inherited markers in the same individuals has rarely been done (Martínez Marignac et al, 2004; Corach et al, 2006; Salas et al, 2008).…”

Population stratification in Argentina strongly influences likelihood ratio estimates in paternity testing as revealed by a simulation-based approach

“…The importance of population substructure in Argentina has been minimized in previous studies [20][21][22][23]. More recently, Marino et al [13] measured the impact of population substructure in Argentina, analyzing 15 autosomal STRs in ten population samples from the country, and concluded that no substructure could be detected supporting that a single database of the whole country could be suitable for the correct interpretation of paternity testing and forensic casework results.…”