Popular over‐the‐counter cosmeceutical ingredients and their clinical efficacy

Tetali, Bhavana; Fahs, Fatima; Mehregan, Darius

doi:10.1111/ijd.14718

Cited by 18 publications

(28 citation statements)

References 31 publications

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“…Compared to tretinoin, retinol is about tenfold less potent [ 10 , 14 ]. For example, retinol at a concentration of 0.25% is considered to be as effective as 0.025% tretinoin, without significant side effects and irritation [ 79 ].…”

Section: Clinical Evidencementioning

confidence: 99%

“…The term cosmeceuticals is used for cosmetic products with active ingredients for which “drug-like” effects on skin structure and function are claimed and are distinguished as a subgroup between cosmetic products and topical prescription medicines [ 13 ]. However, because of their classification as cosmeceuticals, no rigorous pre-market safety or efficacy testing is required [ 14 ]. Because retinoids present as active ingredients in cosmeceuticals must be converted to tretinoin after application, researchers question their efficacy compared to tretinoin [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…However, because of their classification as cosmeceuticals, no rigorous pre-market safety or efficacy testing is required [ 14 ]. Because retinoids present as active ingredients in cosmeceuticals must be converted to tretinoin after application, researchers question their efficacy compared to tretinoin [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations

Milosheska¹,

Roškar

2022

Adv Ther

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Nowadays, numerous skincare routines are used to rejuvenate aging skin. Retinoids are one of the most popular ingredients used in antiaging treatments. Among the representatives of retinoids, tretinoin is considered the most effective agent with proven antiaging effects on the skin and can be found in formulations approved as medicines for topical treatment of acne, facial wrinkles, and hyperpigmentation. Other retinoids present in topical medicines are used for various indications, but only tazarotene is also approved as adjunctive agent for treatment of facial fine wrinkling and pigmentation. The most commonly used retinoids such as retinol, retinaldehyde, and retinyl palmitate are contained in cosmeceuticals regulated as cosmetics. Since clinical efficacy studies are not required for marketing cosmetic formulations, there are concerns about the efficacy of these retinoids.

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Section: Clinical Evidencementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations

Milosheska¹,

Roškar

2022

Adv Ther

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“…These seven picked flora confirm the maximum elevated ability to inhibit the activity of the enzyme tyrosinase [ 40 ]. This prompts the production of GIGAWHITE to be applied as a common and more reliable replacement to hydroquinone for pores and skin in skin lightening merchandise [ 44 ].…”

Section: Bleaching Agentsmentioning

confidence: 99%

Bioactive-Based Cosmeceuticals: An Update on Emerging Trends

et al. 2022

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Cosmetic-containing herbals are a cosmetic that has or is claimed to have medicinal properties, with bioactive ingredients purported to have medical benefits. There are no legal requirements to prove that these products live up to their claims. The name is a combination of “cosmetics” and “pharmaceuticals”. “Nutricosmetics” are related dietary supplements or food or beverage products with additives that are marketed as having medical benefits that affect appearance. Cosmetic-containing herbals are topical cosmetic–pharmaceutical hybrids intended to enhance the health and beauty of the skin. Cosmetic-containing herbals improve appearance by delivering essential nutrients to the skin. Several herbal products, such as cosmetic-containing herbals, are available. The present review highlights the use of natural products in cosmetic-containing herbals, as natural products have many curative effects as well as healing effects on skin and hair growth with minimal to no side effects. A brief description is given on such plants, their used parts, active ingredients, and the therapeutic properties associated with them. Mainly, the utilization of phytoconstituents as cosmetic-containing herbals in the care of skin and hair, such as dryness of skin, acne, eczema, inflammation of the skin, aging, hair growth, and dandruff, along with natural ingredients, such as for hair colorant, are explained in detail in the present review.

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“…Patients may buy cosmeceutical products that dermatologists recommend or sell, as they trust trained dermatology providers to evaluate products objectively. However, many cosmeceuticals are ineffective or untested, 3 and physician recommendations may lead patients to spend money unnecessarily instead of obtaining appropriate treatment. Additionally, monetary relationships between physicians and cosmeceutical companies may foster distrust among the public if patients view their doctors as paid agents of private companies instead of unbiased, highly skilled professionals with their best interests in mind.…”

mentioning

confidence: 99%