Polyvinyl chloride pneumoconiosis.

Arnaud, A; Santi, P P Pommier de; Garbe, L; Payan, H; Charpin, J

doi:10.1136/thx.33.1.19

Cited by 49 publications

(25 citation statements)

References 6 publications

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“…The histological picture was the same as, or close ly resembled, that described by us previously [6]. Ultrastructural studies of the foreign body giant cells in the granulomas revealed intracytoplasmic non-homogenous material [12], resembling that described by us on the base of light microscopic investigation. The granulomatous lesions were associated with interstitial fibrosis of varying severity.…”

Section: Further Evidence Of Pvc Pneumoconiosissupporting

confidence: 67%

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Polyvinyl-Chloride-Induced Lung Disease

Szende¹

1994

Indoor Built Environ

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The first histologically and clinically documented case of pneumoconiosis caused by prolonged polyvinyl chloride (PVC) inhalation was described in 1970. A series of human epidemiological as well as some experimental studies confirmed the existence of PVC pneumoconiosis. Pyrolytic products of PVC, of vinyl chloride and of plasticisers and stabilisers may irritate the respiratory organs, causing fibrosis, asthma, bronchitis and even cancer of the lung. Workers employed in PVC plants are at high risk with respect to PVC-induced lung disease.

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Section: Further Evidence Of Pvc Pneumoconiosissupporting

confidence: 67%

“…Lung biopsy was performed Only in a few cases [12,13]. The histological picture was the same as, or close ly resembled, that described by us previously [6].…”

Section: Further Evidence Of Pvc Pneumoconiosismentioning

confidence: 59%

Polyvinyl-Chloride-Induced Lung Disease

Szende¹

1994

Indoor Built Environ

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“…In 1978, Arnaud et al (36) reported a case of pneumoconiosis in a 53-year-old man who had been exposed to polyvinyl chloride) in the bagging area of a VC polymerization plant. This patient presented with exertional dyspnea, pulmonary function changes, and chest radiographic abnormalities.…”

Section: Products Selikoff Based His Suggestion On the Results Of Stmentioning

confidence: 98%

Toxicity of Vinyl Chloride and Poly(Vinyl Chloride): A Critical Review

Wagoner¹

1983

Environmental Health Perspectives

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“…We could find no published description suggesting that PVC pneumoof fibrosis and conspicuous fibrin in the interstitium, but not some of the features docu-coniosis might regress. This case suggests that in its early stages or after a relatively short mented in heavily dusted experimental animals 6 and in case reports of workers with respiratory exposure, PVC pneumoconiosis is largely reversible. Further longitudinal studies are disease following heavy exposure to PVC who needed before we fully understand the natural history of PVC pneumoconiosis.…”

Section: Pneumoconiosis Clinical and Radiologicalmentioning

confidence: 94%