Polyvinyl alcohol/silver nanoparticles (PVA/AgNps) as a model for testing the biological activity of hybrid materials with included silver nanoparticles

Pencheva, Daniela; Bryaskova, Rayna; Kantardjiev, Todor

doi:10.1016/j.msec.2012.05.016

Cited by 83 publications

(38 citation statements)

References 13 publications

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“…To prevent the connection of small NPs with larger aggregates, the stabilizing agents are used, such as synthetic or natural polymers, for example, polyvinylpyrrolidne, polyvinyl alcohol, polyethylene glycols, chitosan, hydroxyethyl cellulose. Literature reports show that some reducing agents, for example, sodium citrate, act as both the reducing and the stabilizing agent (11)(12)(13)(14)(15)(16)(17).…”

Section: Reviewmentioning

confidence: 99%

The application of differentStevia rebaudianaleaf extracts in the “green synthesis” of AgNPs

Bujak

Nizioł–Łukaszewska

Gaweł-Bęben

et al. 2015

Green Chemistry Letters and Reviews

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The present work reports a method for green synthesis of silver nanoparticles (AgNPs) by reducing Ag ions from silver nitrate solution using alcoholic, aqueous and alcoholic-aqueous Stevia rebaudiana extracts. Depending on a particular extract different sizes of AgNPs could be observed -40 nm in aqueous and aqueous-alcoholic extracts and significantly bigger 170 nm in case of alcoholic extract. Synthesis of AgNPs was analyzed within spectra range of 300-700 nm. The performed research provided information that aqueous and aqueous-alcoholic extracts are excellent sources for synthesis of AgNPs; however AgNPs were unstable in the case of alcoholic extract. The aqueous-alcoholic extract showed the best properties during studies. Antioxidant potential, antimicrobial properties and cytotoxicity were determined. The 2,2-diphenyl-1-(2,4,6-triphenyl-hydrazyl) method showed that antioxidant activity of an extract containing AgNPs was higher compared to Stevia extract alone. Bacterial inhibition studies had shown substantial antibacterial properties of AgNPs, which was much higher than Stevia extract alone and silver nitrate. ARTICLE HISTORY

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Section: Reviewmentioning

confidence: 99%

The application of differentStevia rebaudianaleaf extracts in the “green synthesis” of AgNPs

Bujak

Nizioł–Łukaszewska

Gaweł-Bęben

et al. 2015

Green Chemistry Letters and Reviews

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“…AgNPs have specific properties such as high thermal conductivity and stability [10], and strong shape-dependent optical properties [11,12]. Furthermore, AgNPs are capable of enhancing the scarless wound healing and cosmetic appearance [13,14]. Moreover, AgNPs are considered as one of the most inorganic materials [15].…”

Section: Introductionmentioning

confidence: 99%

Assessment of in situ-Prepared Polyvinylpyrrolidone-Silver Nanocomposite for Antimicrobial Applications

et al. 2017

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Polyvinylpyrrolidone (PVP) is employed in several potential applications, relying of its special chemical and physical properties in addition to its low toxicity and biocompatibility. The aim of this work is to prepare polyvinylpyrrolidone-silver (PVP-Ag) nanocomposite with high inhibiting effect on the microbial growth and low cytotoxicity. In situ prepared small stable spherical silver nanoparticles, with narrow range particle size distribution, were obtained by easy, economical and rapid chemical reduction method. Silver ions were reduced to silver nanoparticles using low amount of sodium borohydride (NaBH4) as a strong reducing agent. PVP-Ag nanocomposite was prepared using PVP as a stabilizing and capping agent. Formation of the spherical silver nanoparticles with mean particle size 5 nm was confirmed by ultraviolet-visible spectroscopy, high resolution transmission electron microscopy, and dynamic light scattering. The inhibiting growth effect of the nanocomposite toward Gram-positive bacteria (Staphylococcus aureus), Gram-negative bacteria (Pseudomonas aeruginosa), and yeast fungus (Candida albicans) were studied. The cytotoxicity of the nanocomposite against BJ1 normal skin fibroblast cell line was tested. Results of this work presented perfect antimicrobial activity of the PVP-Ag nanocomposite towards bacteria and fungi with low cytotoxicity, which may lead to promising applications in skin wound healing.

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“…Systems based on PVA combined with silver have been studied to be used as biosensors, as burn dressings, etc. PVA-Ag systems can present antimicrobial characteristics [13,14] and non-toxicity [15].…”

Section: Introductionmentioning

confidence: 99%

Mechanical properties and in vitro characterization of polyvinyl alcohol-nano-silver hydrogel wound dressings

et al. 2014

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Polyvinyl alcohol (PVA) hydrogels are materials for potential use in burn healing. Silver nanoparticles can be synthesized within PVA hydrogels giving antimicrobial hydrogels. Hydrogels have to be swollen prior to their application, and the common medium available for that in hospitals is saline solution, but the hydrogel could also take up some of the wound's fluid. This work developed gamma-irradiated PVA/nano-Ag hydrogels for potential use in burn dressing applications. Silver nitrate (AgNO 3 ) was used as nano-Ag precursor agent. Saline solution, phosphate-buffered solution (PBS) pH 7.4 and solution pH 4.0 were used as swelling media. Microstructural evaluation revealed an effect of the nanoparticles on PVA crystallization. The swelling of the PVA-Ag samples in solution pH 4.0 was low, as was their silver delivery, compared with the equivalent samples swollen in the other media. The highest swelling and silver delivery were related to samples prepared with 0.50% AgNO 3 , and they also presented lower strength in PBS pH 7.4 and solution pH 4.0. Both PVA-Ag samples were also non-toxic and presented antimicrobial activity, confirming that 0.25% AgNO 3 concentration is sufficient to establish an antimicrobial effect. Both PVA-Ag samples presented suitable mechanical and swelling properties in all media, representative of potential burn site conditions.

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Polyvinyl alcohol/silver nanoparticles (PVA/AgNps) as a model for testing the biological activity of hybrid materials with included silver nanoparticles

Cited by 83 publications

References 13 publications

The application of differentStevia rebaudianaleaf extracts in the “green synthesis” of AgNPs

The application of differentStevia rebaudianaleaf extracts in the “green synthesis” of AgNPs

Assessment of in situ-Prepared Polyvinylpyrrolidone-Silver Nanocomposite for Antimicrobial Applications

Mechanical properties and in vitro characterization of polyvinyl alcohol-nano-silver hydrogel wound dressings

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