Polyunsaturated fatty acids from microalgae Spirulina platensis modulates lipid metabolism disorders and gut microbiota in high-fat diet rats

Maternal Exercise Improves High-Fat Diet-Induced Metabolic Abnormalities and Gut Microbiota Profiles in Mouse Dams and Offspring

“…It has been confirmed that Alloprevotella can produce acetic and succinic acids as end products of fermentation (Downes et al, 2013). A recent study provided evidence that the improved lipid profiles, including a reduction in TG, TC, LDL-C, and hepatic lipid accumulation, induced by polyunsaturated fatty acids supplementation in HFD-fed mice were related with the elevated abundance of Alloprevotella (Li et al, 2019b). The enrichment of Alloprevotella FIGURE 7 | of GTT; BG30, blood glucose level at 30 min of GTT; BG60, blood glucose level at 60 min of GTT; BG120, blood glucose level at 120 min of GTT; AUC, area under the curve of GTT; HOMA-IR, the homeostasis model assessment of insulin resistance; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; and FFA, free fatty-acid.…”

Naringin Attenuates High Fat Diet Induced Non-alcoholic Fatty Liver Disease and Gut Bacterial Dysbiosis in Mice

“…Campylobacter is an opportunistic pathogen that affects host health (Moon et al, 2018). Patients with NAFLD were reported to have increased levels of Bradyrhizobium (Del Chierico et al, 2017), and Turicibacter was positively correlated with lipid metabolism indicators (Li L. et al, 2019;Li T. T. et al, 2019); however, the detailed mechanism by which these bacteria are involved in NAFLD is unclear. Additionally, the effects on lipid metabolism of some bacteria with altered relative abundances, such as Butyricicoccus, Candidatus _ Solibacter, FIGURE 9 | Proposed mechanisms for protective effects of NAR on HFD-fed mice.…”

Bioregional Alterations in Gut Microbiome Contribute to the Plasma Metabolomic Changes in Pigs Fed with Inulin

“…Our results suggest that Faecalibacterium is more abundant in cecum and colon of inulin-fed pigs than con-fed pigs. As a traditional target of inulin [18], Faecalibacterium is well known for conferring health benefits and has been shown to decrease lipid accumulation, improve insulin sensitivity, and increase fatty acid oxidation and adiponectin signaling [41,42]. Moreover, we found that Turicibacter decreased in three gut sites for inulin-fed pigs, an effect which has previously been reported to be correlated with steroid and lipid metabolism [43] and is negatively correlated with protein and energy digestibility in low-fiber feeding growing-finishing pigs [44].…”