2015
DOI: 10.1016/j.foodres.2015.06.043
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Polyphenols-rich fruit in maternal diet modulates inflammatory markers and the gut microbiota and improves colonic expression of ZO-1 in offspring

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Cited by 42 publications
(32 citation statements)
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“…Previous data by our research group using a metabolic programming model revealed that supplementing the diet of pregnant rats with juçara berries (262.4 mg ACN/100 g fresh matter) reduced metabolic and inflammatory markers and increased Lactobacillus and Bifidobacterium spp. expression of genomic DNA and ZO‐1 gene in their offspring, demonstrating that phenolic compounds present in this fruit contribute to the control of inflammation and prevention of the development of chronic diseases through the intestinal pathway up until adulthood .…”
Section: Anthocyanins and Gut Microbiota Modulationmentioning
confidence: 99%
“…Previous data by our research group using a metabolic programming model revealed that supplementing the diet of pregnant rats with juçara berries (262.4 mg ACN/100 g fresh matter) reduced metabolic and inflammatory markers and increased Lactobacillus and Bifidobacterium spp. expression of genomic DNA and ZO‐1 gene in their offspring, demonstrating that phenolic compounds present in this fruit contribute to the control of inflammation and prevention of the development of chronic diseases through the intestinal pathway up until adulthood .…”
Section: Anthocyanins and Gut Microbiota Modulationmentioning
confidence: 99%
“…found that supplementation with anthocyanins‐rich jussara powder normalized the increased body weight, serum TC, TG, and restored intestine bacteria of Bifidobacterium and Lactobacillus in trans fatty acid diet feeding rats. [ 7,8 ] Moreover, the intestine bacteria of Bifidobacterium and Lactobacillus have been found to exert a vital role in β‐glucosidase and bile salt hydrolase activity with the ability to transform anthocyanins to phenolic acids, produce SCFAs, lower serum cholesterol, and increase fecal sterol excretion. [ 9–11 ] Furthermore, SCFAs fermented by the gut microbiota are beneficial to gut health by enhancing gut barrier function, increasing mucus secretion, and modulating lipid metabolism.…”
Section: Introductionmentioning
confidence: 99%
“…Our research has taken into account physiological doses of jussara preserving the safety of pregnant mothers. This can also be seen in our previous studies [31,32]. Our research took into account the dose of jussara consumed by human subjects [49].…”
Section: Discussionmentioning
confidence: 52%
“…), which is rich in anthocyanins and native species of the Atlantic Rainforest/Brazil [30]. Our research has shown promising effects of jussara fruit supplementation on the metabolic programming of the colon, hypothalamus and white adipose tissues in the offspring [31,32]. However, studies on the impact of the bioactive food compound supplementation on the programming models in the BAT are less common in the literature.…”
Section: Introductionmentioning
confidence: 78%