Contribution of anthocyanin‐rich foods in obesity control through gut microbiota interactions

Abstract

Obesity is characterized by low-grade inflammation and a number of metabolic disorders. Distal gut microbes' content (microbiota) is not yet fully understood but evidence shows that it is influenced by internal and external factors that modulate its composition and function. The evidence that gut microbiota composition can differ between healthy and obese individuals, as well as for those who maintain specific dietary habits, has led to the study of this environmental factor as a key link between the pathophysiology of obesity and gut microbiota. Data obtained about the role of anthocyanins (ACNs) in microbiota may lead to different strategies to manipulate bacterial populations and promote health. Anthocyanins have been identified as modulators of gut microbiota that contribute to obesity control and these bioactive compounds should be considered to have a prebiotic action. This review addresses the relevance of knowledge about the influence of anthocyanins-rich food consumption on microbiota, and their health-promoting potential in the pathophysiology of obesity. © 2017 BioFactors, 43(4):507-516, 2017.

Hydroxycinnamic acids and human health: recent advances

“…Data describing the effect of HCAs on the gut microbiota are scarce compared to other classes of phenolics, e.g. anthocyanins . Therefore, a summary of recent studies (pre‐clinical and clinical) and the effect of HCAs on gut microbiota is given below.…”

“…anthocyanins. [236][237][238][239][240] Therefore, a summary of recent studies (pre-clinical and clinical) and the effect of HCAs on gut microbiota is given below.…”

Protective Effects of Anthocyanins in Obesity‐Associated Inflammation and Changes in Gut Microbiome

“…Accordingly, compared to lean individuals, obese individuals show a remarkable tenfold shift in the ratio from 3:1 to 35:1 of Firmicutes to Bacteroidetes phyla in the human GI tract . Moreover, when obese subjects lose weight, the abundance of Firmicutes is reduced and becomes more similar to that in lean individuals . The changes of gut microbiota during obesity are shown in Table .…”

“…, and Akkermansia muciniphila spp ., and decrease the colonization of harmful bacterium Clostridium histolyticum . Both anthocyanins and microbiota metabolites have protective effects against fat accumulation and are effective in inhibiting inflammation by attenuating LPS‐induced translocation of NF‐kB …”

“…[92] Moreover, when obese subjects lose weight, the abundance of Firmicutes is reduced and becomes more similar to that in lean individuals. [111] The changes of gut microbiota during obesity are shown in Table 4.…”