Polyphenols, carotenoids, and ascorbic acid in underutilized medicinal vegetables

Andarwulan, Nuri; Kurniasih, Dewi; Apriady, Riza Aris; Rahmat, Hardianzah; Roto, Anna V; Bolling, Bradley W.

doi:10.1016/j.jff.2012.01.003

Cited by 149 publications

(133 citation statements)

References 27 publications

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“…8 Root extract of Sophora flavescens has been reported to stimulate hair growth. [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] In this study, formula II and III, each containing 0.5% and 1% of ethyl acetate fraction have faster hair growth than positive control (Figure 1). The mechanism of hair growth from the ethyl acetate fraction is still unclear, but the activity of hair growth resulting from the ethyl acetate fraction N. scutellarium leaves is suggested due to flavonoids.…”

Section: Hair Lengthmentioning

confidence: 85%

“…28 The role of flavonoids on the activity of hair growth is caused by several factors hair growth, such as insulin-like growth factors-1 (IGF-1), vascular endothelial growth factors (VEGF), keratinocyte growth factors (KGF), and hepatocyte growth factors (HGF), these factors have the effect of stimulating hair growth. 8,[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] In this study, the hair tonic on the formula III has a larger diameter than the positive control and has hair cuticle composed regularly and overlap (Figure 4). Some research suggests that healthy hair is observed with SEM (Scanning Electron Microscope) can be seen clearly has the hair cuticle smooth edges, patterns of cuticle layer to are arranged neatly to the inside of the hair seemed protected.…”

Section: Hair Lengthmentioning

confidence: 90%

“…Flavonoid has been reported to have some pharmacological activities, such as antioxidant, hepatoprotective and anticancer. 18,19,20 Based on several studies, a compound that plays a role in hair growth activity are proanthocyanidin compounds and procyanidin. 8,21 One of the mechanisms hair growth promoting through Endothelial nitric oxide synthase (eNOS).…”

Section: Discussionmentioning

confidence: 99%

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Hair Growth Promoting Activity of Nothopanax scutellarium Merr. Leaves

Rifkia¹,

Jufri²,

Mun’im³

2017

JYP

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Objective: The aims of this study were to know the safety using Hen's eggs-chorioallantoic membrane (HET-CAM) test method and hair growth promoting activity of the ethyl acetate fraction of Nothopanax scutellarium leaves. Methods: Safety test was measured by scoring and categorizing irritation onHET-CAM. Meanwhile, activity test was conducted by applying the hair tonic of the ethylacetate fraction on the back of the rabbits, and the length of hair was measured in the 1 st , 2 nd and 3 rd week.In the 3 rd week, the hair growth was weighed and hair diameter also was measuredusing scanning electron microscope (SEM). Results:The result showed that 0.2 gram of ethyl acetate fraction of N.scutellarium leaves have mild irritation effect, whereas the formulation contained with 0.5% and 1% of fraction increased hair growth and hair diameter. Conclusion: The ethyl acetate fraction of N. scutellarium have mild irritan effect, and the hair tonic demonstrated hair growth promoting activity.

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Section: Hair Lengthmentioning

confidence: 85%

Section: Hair Lengthmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

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Hair Growth Promoting Activity of Nothopanax scutellarium Merr. Leaves

Rifkia¹,

Jufri²,

Mun’im³

2017

JYP

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“…Esses carotenóides presentes nos vegetais por sua vez também possuem funções antioxidantes, prevenindo deficiências de vitamina A e quando consumido com lipídios, apresentam uma maior biodisponibilidade (Andarwulan et al, 2012). Em termos nutricionais alguns carotenóides são fonte de vitamina A (Cooper, 2004).…”

Section: Carotenóidesunclassified

“…Os vegetais folhosos ou não folhosos de modo geral estudados por Kunyanga et al (2012) apresentaram um perfil qualitativo quanto aos teores de carotenóides, tais como a luteína, o β-caroteno, a violaxantina e a neoxantina os principais. De acordo com Andarwulan et al (2012) os teores de carotenóides totais mais elevados, foram em torno de 13,96 mg de β-caroteno por 100g. Segundo as pesquisas realizadas por Lako et al (2007) os teores de β-caroteno observados nas folhas de Moringa oleifera cozida a vapor foram de 340 μg por grama e para folhas ferventadas e de 280μg por grama.…”

Section: Carotenóidesunclassified

Uso da moringa na alimentação animal e humana: Revisão

Marinho¹,

Arruda²,

Fernandes

et al. 2016

Pubvet

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RESUMO.A moringa é uma planta de indiscutível importância econômica na indústria alimentícia e farmacêutica. Suas folhas frescas possuem excelentes qualidades nutricionais, sendo uma boa fonte protéica (33,8% de proteína bruta), além de conter em sua composição as vitaminas A, B e C, os minerais como, ferro, cálcio, fósforo e potássio e dispor de uma boa digestibilidade (em média 79,7%), o que a configura como um bom suplemento para animais. É considerada uma fonte valiosa de carotenóides e de compostos bioativos, com atividade hipotensiva e antioxidante. Das sementes pode ser extraído o óleo que apresenta 37,2% de lipídeos, contendo baixo conteúdo de ácidos graxos poli-insaturados (<1%) e desta forma alta resistência à oxidação, pela presença de elevados teores de ácidos graxos insaturados, especialmente o oléico, sendo o palmítico e o bezênico, os ácidos graxos saturados dominantes. O cultivo dessa planta em regiões secas pode ser uma estratégia alimentar bastante vantajosa, uma vez que suas folhas podem ser colhidas quando nenhum outro vegetal verde se apresenta disponível. Desta forma, considerando-se o crescente interesse no uso de alimentos naturais e que forneçam, além de nutrientes, compostos bioativos, apresentamos uma revisão sobre a moringa e suas principais formas de utilização na alimentação animal e humana. Palavras chave: Antioxidantes, ácidos graxos, compostos bioativos, Moringa oleiferaUse of moringa in animal and human nutrition: Review ABSTRACT. Moringa is an indisputable economic importance in plant food and pharmaceutical industry. Its fresh leaves have excellent nutritional value, is a good source of protein (33.8% crude protein), and contain in its composition vitamin A, B and C, minerals such as iron, calcium, phosphorus and potassium and have good digestibility (average 79.7%), which configures as a good supplement for animals. It is considered a valuable source of carotenoids and bioactive compounds with hypertensive and antioxidant activity. Seeds can be extracted from the oil which has 37.2% lipids, containing low content of polyunsaturated fatty acids (<1%) and therefore high oxidation resistance, by the presence of high levels of unsaturated fatty acids, especially oleic, and palmitic and bezenic, the dominant saturated fatty acids. The cultivation of this plant in dry are as can be quite advantageous dietary strategy, since its leaves can be harvested when no other vegetable presents available. Thus, considering the growing interest in the use of natural foods and provide, in addition to nutrients, bioactive compounds, present a review of the moringa and its main forms of use for animal and human nutrition.

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Melanogenesis‐Inhibitory and Cytotoxic Activities of Chemical Constituents from the Leaves of Sauropus androgynus L. Merr. (Euphorbiaceae)

Zhang

Zhu

et al. 2018

Chemistry & Biodiversity

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A new steroid, 20-hydroxyisofucosterol (stigmasta-5,24(28)-diene-3β,20β-diol) (7), along with six known compounds 1 - 6 were isolated from the MeOH extract of the leaves of Sauropus androgynus L. Merr. (Euphorbiaceae). The structure of new steroid was determined by HR-APCI-MS and various NMR techniques in combination with literature data. Subsequently, their anti-inflammatory, cytotoxic activities against five human cell lines, as well as inhibitory activities against the α-MSH induced melanogenesis on the B16 cell line were evaluated. As the results, steroid compounds, 6 and 7 exhibited moderate cytotoxic to HL60, AZ521, SKBR3, and A549 tumor cell lines (IC 26.9 - 45.1 μm) with high tumor selectivity for A549 relative to WI38 cell lines (SI 2.6 and 3.0, resp.). And, flavonoid compounds, 4 and 5 exhibited superior inhibitory activities against melanogenesis (67.0 - 94.7% melanin content), even with no or low toxicity to the cells (90.1 - 99.6% cell viability) at the concentrations from 10 to 100 μm. Furthermore, Western blot analysis suggested that compound 5 could inhibit melanogenesis by suppressing the protein expressions of MITF, TRP-1, TRP-2, and tyrosinase.

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Polyphenols, carotenoids, and ascorbic acid in underutilized medicinal vegetables

Cited by 149 publications

References 27 publications

Hair Growth Promoting Activity of Nothopanax scutellarium Merr. Leaves

Hair Growth Promoting Activity of Nothopanax scutellarium Merr. Leaves

Uso da moringa na alimentação animal e humana: Revisão

Melanogenesis‐Inhibitory and Cytotoxic Activities of Chemical Constituents from the Leaves of Sauropus androgynus L. Merr. (Euphorbiaceae)

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