Polyphenols as natural antioxidants in cosmetics applications

Cherubim, Débora Jackeline de Lima; Martins, Cleide Viviane Buzanello; Fariña, Luciana Oliveira de; Lucca, Rosemeire Aparecida da Silva de

doi:10.1111/jocd.13093

Cited by 207 publications

(114 citation statements)

References 34 publications

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“…Oxidative stress is strongly associated with skin aging because of the progressive accumulation of ROS in skin, as age increases [103]. Natural antioxidants are used in the production of pharmaceutical or cosmetic formulations with the aim of delaying the skin aging process and ameliorating skin aesthetics [104]. Gnetum gnemon (melinjo) is an arboreal dioecious plant extensively cultivated in South Asia.…”

Section: Intrinsic Aging and Cosmetic Usementioning

confidence: 99%

The Bioactivities of Resveratrol and Its Naturally Occurring Derivatives on Skin

Lin¹,

Hung²,

Sung³

et al. 2021

Journal of Food and Drug Analysis

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Resveratrol has been extensively reported as a potential compound to treat some skin disorders, including skin cancer, photoaging, allergy, dermatitis, melanogenesis, and microbial infection. There has been an increasing interest in the discovery of cosmetic application using resveratrol as the active ingredient because of its anti-aging and skin lightening activities. The naturally occurring derivatives of resveratrol also exert a beneficial effect on the skin. There are four groups of resveratrol derivatives, including hydroxylated compounds, methoxylated compounds, glycosides, and oligomers. The major mechanism of resveratrol and its derivatives for attenuating cutaneous neoplasia, photoaging and inflammation, are related with its antioxidative activity to scavenge hydroxyl radical, nitric oxide and superoxide anion. A systematic review was conducted to describe the association between resveratrol-related compounds and their benefits on the skin. Firstly, the chemical classification of resveratrol and its derivatives was introduced. In this review the cases which were treated for different skin conditions by resveratrol and the derivatives were also described. The use of nanocarriers for efficient resveratrol skin delivery is also introduced here. This review summarizes the cutaneous application of resveratrol and the related compounds as observed in the cell-based, animal-based and clinical models. The research data in the present study relates to the management of resveratrol for treating skin disorders and suggesting a way forward to achieve advancement in using it for cosmetic and dermatological purpose.

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Section: Intrinsic Aging and Cosmetic Usementioning

confidence: 99%

The Bioactivities of Resveratrol and Its Naturally Occurring Derivatives on Skin

Lin¹,

Hung²,

Sung³

et al. 2021

Journal of Food and Drug Analysis

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“…141 Even though not being recognized as a term, cosmeceuticals refers to cosmetics that deliver a physiological skin benefit through either pure chemicals or natural active ingredients. [142][143][144][145][146] These are being used in anti-aging, barrier function improvement, anti-inflammatories, UV/pollution protection, and moisturization.…”

Section: Beauty Routinementioning

confidence: 99%

The Skin Interactome: A Holistic “Genome-Microbiome-Exposome” Approach to Understand and Modulate Skin Health and Aging

Khmaladze¹,

Leonardi²,

Fabre³

et al. 2020

CCID

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Higher demands on skin care cosmetic products for strong performance drive intense research to understand the mechanisms of skin aging and design strategies to improve overall skin health. Today we know that our needs and influencers of skin health and skin aging change throughout our life journey due to both extrinsic factors, such as environmental factors and lifestyle factors, as well as our intrinsic factors. Furthermore, we need to consider our microflora, a collection of micro-organisms such as bacteria, viruses, and fungi, which is a living ecosystem in our gut and on our skin, that can have a major impact on our health. Here, we are viewing a holistic approach to understand the collective effect of the key influencers of skin health and skin aging both reviewing how each of them impact the skin, but more importantly to identify molecular conjunction pathways of these different factors in order to get a better understanding of the integrated “genome-microbiome-exposome” effect. For this purpose and in order to translate molecularly the impact of the key influencers of skin health and skin aging, we built a digital model based on system biology using different bioinformatics tools. This model is considering both the positive and negative impact of our genome (genes, age/gender), exposome: external (sun, pollution, climate) and lifestyle factors (sleep, stress, exercise, nutrition, skin care routine), as well as the role of our skin microbiome, and allowed us in a first application to evaluate the effect of the genome in the synthesis of collagen in the skin and the determination of a suitable target for boosting pro-collagen synthesis. In conclusion, we have, through our digital holistic approach, defined the skin interactome concept, as an advanced tool to better understand the molecular genesis of skin aging and further develop a strategy to balance the influence of the exposome and microbiome to protect, prevent, and delay the appearance of skin aging signs and preserve good skin health condition. In addition, this model will aid in identifying and optimizing skin treatment options based on external triggers, as well as helping to design optimal treatments modulating the intrinsic pathways.

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“…The use of natural polyphenols in cosmetics is justified and worthwhile due to their capability to ameliorate cutaneous issues and applicability for antiaging purposes in cosmetics, as well as for nutraceutical applications. Natural polyphenols possess the potential to prevent premature ageing, decrease the occurrence of skin cancer, attenuate photoaging and protect skin against ultraviolet radiation [ 9 ]. Furthermore they have properties of depigmenting, impairing inflammation, healing wounds and mitigating skin irritation [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Chrząszcz

Krzemińska

Skowronek

et al. 2021

Plants

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The genus Cephalaria, belonging to the Caprifoliaceae family, is a rich source of interesting secondary metabolites, including mainly saponins which display a variety of biological activities, such as immunomodulatory, antimicrobial and hemolytic effects. Besides these compounds, flavonoids and phenolic acids were identified in Cephalaria species. Cephalaria is employed in traditional medicine e.g., to cure cardiac and lung diseases, rheumatism, and regulate menstruation. In this review we focus on the phenolic compound composition and antioxidative activity of Cephalaria species. The antioxidant effect can be explained by flavonoids present in all parts of these plants. However, future efforts should concentrate more on in vitro and in vivo studies and also on clinical trials in order to confirm the possibility of using these plants as natural antioxidants for the pharmacology, food or cosmetic industries.

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Polyphenols as natural antioxidants in cosmetics applications

Cited by 207 publications

References 34 publications

The Bioactivities of Resveratrol and Its Naturally Occurring Derivatives on Skin

The Bioactivities of Resveratrol and Its Naturally Occurring Derivatives on Skin

The Skin Interactome: A Holistic “Genome-Microbiome-Exposome” Approach to Understand and Modulate Skin Health and Aging

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

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