Polypharmacy Among Adults Aged 65 Years and Older in the United States: 1988–2010

Charlesworth, Christina J.; Smit, Ellen; Lee, David S. H.; Alramadhan, Fatimah; Odden, Michelle C.

doi:10.1093/gerona/glv013

Cited by 474 publications

(407 citation statements)

References 24 publications

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“…In developed countries, polypharmacy among the elderly varied between 39% 5 and 45% of the population 6 . In Brazil, a study with elderly people living in the metropolitan area of the city of São Paulo found a prevalence of polypharmacy of 36.0% 2 .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of and factors associated with polypharmacy among elderly persons resident in the community

Almeida¹,

Reiners

Azevedo

et al. 2017

Rev. bras. geriatr. gerontol.

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Objective: to verify the prevalence of and factors associated with polypharmacy among elderly residents of the city of Cuiabá, in the state of Mato Grosso. Method: a cross-sectional study of 573 people aged 60 and over was performed. Polypharmacy was defined as the use of five or more medications. To investigate the association between polypharmacy and sociodemographic variables, health and access to medication, the Mantel Haenszel chi square test was used in bivariate analysis and Poisson regression was used in multivariate analysis. The significance level adopted was 5%. Result: the prevalence of polypharmacy was 10.30%. Statistically significant associations were found between polypharmacy and living with others, describing suffering from circulatory, endocrine, nutritional and digestive tract diseases, and referring to financial difficulties for the purchase of medicines. Conclusion: some social and health condition factors play an important role in the use of multiple medications among the elderly.

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Section: Introductionmentioning

confidence: 99%

Prevalence of and factors associated with polypharmacy among elderly persons resident in the community

Almeida¹,

Reiners

Azevedo

et al. 2017

Rev. bras. geriatr. gerontol.

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“…1,3 Polypharmacy has become more common among the elderly 4 and is related to several problems, including increased risk of being prescribed potentially inappropriate medications (PIMs), 5 which are delineated in several drug lists, such as the American Geriatrics Society Beers criteria. 6 Both polypharmacy and PIMs increase adverse drug events, worsen physical function, and result in excess health care utilization.…”

mentioning

confidence: 99%

Physician Factors Associated with Polypharmacy and Potentially Inappropriate Medication Use

Felton

Springer

et al. 2017

J Am Board Fam Med

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Background: Despite accumulating evidence about the harm of polypharmacy in family medicine, few studies have investigated factors related to polypharmacy. The objective of this study was to explore factors related to physicians' prescribing behavior.Methods: We conducted a survey of physicians at 5 family medicine residency practices and a linked health record review of their patients >65 years old. The determinants of physicians' mean number of prescriptions and potentially inappropriate medications (PIMs) were examined using a generalized linear model.Results: A total of 61 physicians (38 residents, 23 fellows/faculty) completed the survey, and 2103 visits by 932 patients seen by these physicians were analyzed. The mean numbers of prescriptions and PIMs per visit per physician were 9.50 and 0.46, respectively. After controlling for patient race and age, low prescribers were more likely to consider the number of medications (P ‫؍‬ .007) and benefit/risk information for deprescribing (P ‫؍‬ .017) when making prescribing decisions. Use of the Beers List was marginally significant in lower PIM prescribing (P ‫؍‬ .05). Physicians' sex, duration of experience, and perceived confidence were not associated with prescribing patterns.Conclusions: Conscious consideration concerning the number of medications and benefit/risk information, as well as using the Beers List, were associated with less polypharmacy and fewer PIMs. (J Am Board Fam Med 2017;30:528 -536.)

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“…The single greatest predictor of ADEs and high-risk prescribing is the number of medicines a person is taking [10]. With demographic ageing, there are increasing numbers of older people prescribed multiple medications for multiple co-existing medical conditions [11]. In New…”

Section: High-risk Prescribingmentioning

confidence: 99%

Safer Prescribing and Care for the Elderly (SPACE): Protocol of a Cluster Randomized Controlled Trial in Primary Care (Preprint)

Wallis¹,

Elley²,

Lee³

et al. 2018

Preprint

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Polypharmacy Among Adults Aged 65 Years and Older in the United States: 1988–2010

Abstract: Prescription medication use increased dramatically among older adults between 1988 and 2010. Contemporary older adults on multiple medications have worse health status compared with those on less medications, and appear to be a vulnerable population.

Cited by 474 publications

References 24 publications

Prevalence of and factors associated with polypharmacy among elderly persons resident in the community

Prevalence of and factors associated with polypharmacy among elderly persons resident in the community

Physician Factors Associated with Polypharmacy and Potentially Inappropriate Medication Use

Safer Prescribing and Care for the Elderly (SPACE): Protocol of a Cluster Randomized Controlled Trial in Primary Care (Preprint)

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