Polyostotic cortical hyperostosis in an 8‐week‐old cat with a 3‐year follow‐up

Abstract

A 2 month-old female cat, mixed breed, was referred for difficulty moving and severe enlargement of the mandible and limbs. Polyostotic cortical hyperostosis was diagnosed based on diagnostic imaging and histopathological changes of the mandible and limbs. Marked cortical bone thickening was detected on radiographs and CT scan images. The diaphyses of both radii and ulnae, together with the mandibular rami and bodies, were most severely affected. The many similarities shared with the human condition, Caffey's disease, are discussed.

Structure and Pathologies of Articular Cartilage

“…For reasons yet to be discovered, it triggers periosteal response and formation of individual or multiple osteochondral outgrowths (exostoses, osteophytes, enthesophytes). They usually emerge in spinal, mainly cervical and thoracic, joints and cause spondylopathies (52)(53)(54), but can also form around large joints such as knees or elbows (e.g. in the intrapatellar fat body).…”