Polymyositis in childhood as clinical manifestation associated with HTLV-1

Ferreira, Ayrton Silva; Costa, Carlos Maurício de Castro; Dantas, Irna Kaden de Sousa; Santos, Terezinha de Jesus Teixeira; Costa, Samuel Bovy de Castro; Câmara, Carlos Campos; Oriá, Reinaldo B.; Gondim, Francisco de Assis Aquino

doi:10.1590/s0004-282x2010000600025

Cited by 2 publications

(1 citation statement)

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“…Polymyositis, dermatomyositis and sporadic inclusion body myositis are uncommon but have been reported in HTLV-1 infected adults and children [53,176,177]. The first case was reported in 1989 in a Haitian woman with myelopathy, myositis and SS living in Clichy, France [178].…”

Section: Htlv-1 Associated Inflammatory Myositismentioning

confidence: 99%

Inflammatory manifestations of HTLV-1 and their therapeutic options

Martin

Taylor

Jacobson

2014

Expert Review of Clinical Immunology

101

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Human T lymphotropic virus type 1 (HTLV-1) is one of the most intriguing retroviruses infecting humans. Most commonly, infection remains undetected, since it does not cause obvious harm, yet in 4-9% of patients, this infection can be devastating, causing adult T-cell leukemia/lymphoma and/or HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). This review concentrates on all inflammatory aspects of HTLV-1 infection: HAM/TSP, HTLV-1 associated uveitis, HTLV-1 associated conjunctivitis, sicca syndrome and interstitial keratitis, HTLV-1 associated Sjö gren's syndrome, Hashimoto's thyroiditis and Graves' disease, HTLV-1 associated pulmonary disease, infective dermatitis associated with HTLV-1, HTLV-1 associated inflammatory myositis and HTLV-1 associated arthritis. With the exception of HAM/TSP treatment, studies of these conditions are sparse and even for HAM/TSP, the level of evidence is limited. While control or elimination of infection remains a goal, most therapy beyond symptomatic management is directed at the immune response to HTLV-1.

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Section: Htlv-1 Associated Inflammatory Myositismentioning

confidence: 99%