Polymorphous Light Eruptions

An Optimal Method for Experimental Provocation of Polymorphic Light Eruption

“…The early PLE induction studies reported success rates from as low as 10% to 30% [6][7][8] to as high as 60% to 95%. [9][10][11] These studies were based on one or more exposures of a single test site to between 1 and 10 times the minimal erythemal dose (MED) of nominal UV-B radiation (ie, 290-320 nm), although these sources almost certainly contained other UVR wavelengths. Initially, induction was achieved with UV-B, [6][7][8][9][10][11][12][13] but several authors also succeeded in reproducing PLE lesions with UV-A irradiation (320-400 nm).…”

Polymorphous light eruption

“…Though in the North and Central American Indian and Finnish populations, a much higher familial relationship has been noted (1,5,6). Many investigators consider the process in the American Indian a different entity.…”

Contralum and the Pathogenetic Wave-lengths in Chronic Polymorphous Lightdermatoses

“…Wiskemann and W ulf (1959) found 28 patients with chronic light dermatoses to be sensitive to at least part of the long-wave UVAspectrum (315-400 mg), which does not cause sunburn in normal subjects; some patients were even sensitive to visible light (above 400 m g). Langhof and Sprôssig had already suggested abnorm al reactions to the UVA-spectrum previously (1954) and Stevanovic (1960) Scott andMolhuysen-van der Walle (1958), Calm et al (1959) and Epstein (1962).…”