1997
DOI: 10.1111/j.1600-0781.1997.tb00121.x
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Polymorphous light eruption

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Cited by 18 publications
(12 citation statements)
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References 11 publications
(6 reference statements)
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“…Because of the clear delay between sunlight exposure and the onset of skin lesions, PLE is often suggested to be a delayed-type (type IV) of hypersensitivity (DTH) reaction. The histological appearance of dense superficial and perivascular dermal lymphocytic infiltrates in skin of PLE patients further supports this (Norris et al, 1992;Verheyen et al, 1995;Epstein, 1997).UV radiation, in particular the UVB range (280-315 nm), suppresses the skin immune response (Duthie et al, 1999). In PLE patients, however, UV exposure seems to result in an activation of the skin immune response.…”
mentioning
confidence: 59%
“…Because of the clear delay between sunlight exposure and the onset of skin lesions, PLE is often suggested to be a delayed-type (type IV) of hypersensitivity (DTH) reaction. The histological appearance of dense superficial and perivascular dermal lymphocytic infiltrates in skin of PLE patients further supports this (Norris et al, 1992;Verheyen et al, 1995;Epstein, 1997).UV radiation, in particular the UVB range (280-315 nm), suppresses the skin immune response (Duthie et al, 1999). In PLE patients, however, UV exposure seems to result in an activation of the skin immune response.…”
mentioning
confidence: 59%
“…PLE is a common chronic idiopathic photodermatosis. Its clinical presentation and history are typical, and it can be easily differentiated from photoprovoked dermatosis and photoallergic disorders [1, 2, 3, 4, 5]. In our series of patients and in other studies, the papular and papular-vesicular presentation covers approximately 80% of all patients.…”
Section: Discussionmentioning
confidence: 82%
“…The UV action spectrum is controversially discussed. Some authors reported that UVA is the wavelength that induces the specific skin lesions in most patients [5, 8, 9]. Other authors also found a significant number of positive tests for the UVB spectrum [2, 10, 11, 12].…”
Section: Introductionmentioning
confidence: 93%
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