Polymerized high internal phase emulsion monolithic material: a novel stationary phase of thin layer chromatography

Abstract

PolyHIPE monolith plate with macroporous structure was prepared and employed for thin layer chromatograph to identify ingredients successfully.

Ecofriendly densitometric RP-HPTLC method for determination of rivaroxaban in nanoparticle formulations using green solvents

“…[29][30][31] Green HPTLC technique offers several advantages over routine HPTLC in the analysis of drugs or pharmaceutical compounds. [32][33][34] Interestingly, no eco-friendly analytical methodology had been applied yet for the analysis of rivaroxaban in pharmaceutical formulations or biological uids. Moreover, no reports on the determination of rivaroxaban biomarker in nanoparticles (NPs) formulation utilizing the RP-HPLC technique are available in the literature so far.…”

Heparin‐Immobilized Polymeric Monolithic Column with Submicron Skeletons and Well‐Defined Macropores for Highly Efficient Purification of Enterovirus 71

“…Large cavities lead to limited specific surface area (typically 3-20 m 2 g −1 , made without special treatment). [18,19] As a result, many applications will be confined, especially for catalysis and separation science where the application relies on the intimate contact between molecules and surface-anchored active sites. [20] If highly porous materials can be generated with homogeneously small-sized skeletons,…”

“…Typically, traditional polyHIPE possesses large spherical cavities with interconnecting holes on the wall. Large cavities lead to limited specific surface area (typically 3–20 m 2 g −1 , made without special treatment) . As a result, many applications will be confined, especially for catalysis and separation science where the application relies on the intimate contact between molecules and surface‐anchored active sites .…”

Robust open cellular porous polymer monoliths made from cured colloidal gels of latex particles

“…For example, pumping the gels into column housing could enable their use for chromatography, 14 or as catalytic supports, [4][5][6][7] while the flat sheet format could be useful for the manufacture of plates for thin-layer chromatography (TLC). 16 The freestanding nature of these gels is particularly advantageous as it provides the possibility of preparing these materials without a mould (Fig. 9C & D), which is not possible when using a porogenic solvent.…”

“…Since their development in the 1990s 1,2 polymer monoliths with an interconnected network of pores have attracted significant attention, in particular as materials for solid phase chemistry, 3 as catalytic supports, [4][5][6][7][8] metal chelating agents, 9 tissue engineering scaffolds, 10,11 controlled release devices, 12 absorbents, 13 chromatography, 2,3,[14][15][16] and for extraction and sample preparation. 9,[17][18][19] The polymer monoliths are characterised as a permanently rigid continuous piece of material with an open cellular porous structure, which allows fluid to flow through.…”